Senior Preclinical Study Manager

Revolution Medicines, Inc.; United States; On-site; USD 150,000 - 189,000; Full time

Job summary

Revolution Medicines is seeking a Preclinical Study Manager to oversee GLP and non-GLP toxicology studies, coordinating with CROs and internal experts to ensure scientific and regulatory objectives are met.

Based onsite in Redwood City, CA, the role offers a base pay range of $150,000–$189,000 USD per year, with responsibilities including protocol reviews, milestone tracking, and cross-functional collaboration across QA, Regulatory, and Project Management. Some travel may be required.

Qualifications

• Experience managing day-to-day study activities with CROs and internal experts to design and monitor GLP and Non-GLP toxicology studies.
• Assistance in protocol and report review for external studies to ensure high-quality CRO deliverables.
• Coordinate nonclinical study activities with toxicologists and internal groups to meet program needs and timelines.
• Track nonclinical milestones against project goals; participate in regulatory submissions.

Responsibilities

• Manage day-to-day study activities with CROs and internal experts.
• Assist toxicologists in protocol and report reviews for external studies.
• Coordinate nonclinical studies with cross-functional teams (PM, CMC, Bioanalytical, Regulatory, Finance, Legal).
• Track milestones against project goals and timelines.
• Support regulatory submissions and preparation/review of nonclinical sections in IBs/NDAs/BLAs.
• Develop and maintain relationships with study directors and collaborators.
• Work with QA on CRO vendor selection and audits.
• Negotiate contracts/SOWs and approval processes.
• Support SOPs, policies, and guidelines development.

Skills

Study coordination

CRO liaison

Regulatory submissions

Project management

ICH/FDA knowledge

Education

BS degree in science

Job description

Revolution Medicines is seeking a Preclinical Study Manager to oversee GLP and non-GLP toxicology studies, coordinating with CROs and internal experts to ensure scientific and regulatory objectives are met.

Based onsite in Redwood City, CA, the role offers a base pay range of $150,000–$189,000 USD per year, with responsibilities including protocol reviews, milestone tracking, and cross-functional collaboration across QA, Regulatory, and Project Management. Some travel may be required.