Senior Platform Biology Research Associate

Deep Genomics; Cambridge (MA); On-site; USD 115,000 - 135,000; Full time

Benefits offered by this job

Stock ownership

Health, vision, and dental coverage

Flexible work environment

Job summary

Deep Genomics is seeking a Principal Research Associate to advance our AI RNA therapeutics discovery platform. You will design and execute cell-based assays, culture mammalian cells, and analyze RNA/protein readouts as part of our internal therapeutic pipeline.

The role requires strong cell biology expertise, hands-on experience with primary cells, and collaboration across cross-functional teams in a fast-paced environment.

Qualifications

• BS or MS in Biology, Molecular Biology, Genomics, Biochemistry or a related field with 4+ years of relevant pharmaceutical or biotechnology experience.
• Hands-on experience growing, maintaining and transfecting mammalian cell lines.
• Strong understanding of molecular and cell biology.
• Experience designing and executing molecular and cellular assays, with ELN documentation.

Responsibilities

• Design, optimise and execute robust cell-based assays, to support compound screens and lead optimisation.
• Culture, maintain and transfect a variety of mammalian cell lines, such as immortalized cell lines, primary cells and co-culture systems, and onboard new cell types and systems to enable drug discovery.
• Examine important molecular and functional endpoints in vitro, including RNA and protein readouts, to better understand our molecules in our internal therapeutic pipeline.
• Perform standard molecular biology techniques (e.g. PCR, qPCR, Jess/Leo Automated Westerns, ELISA, Western blot, etc.).
• Collaborate with a cross-functional team in a dynamic, matrixed environment to achieve shared company deadlines, and communicate experimental design and findings with colleagues and project teams.
• Clearly document experiments, standard operating procedures (SOPs) and data in an electronic lab notebook (ELN).

Skills

Cell biology

Mammalian cell culture

ELN documentation

Scientific communication

Education

BS/MS in Biology

Tools

qPCR

Western blot (Jess/Leo)

ELISA

Beckman Echo / STAR

Job description

Deep Genomics is seeking a Principal Research Associate to advance our AI RNA therapeutics discovery platform. You will design and execute cell-based assays, culture mammalian cells, and analyze RNA/protein readouts as part of our internal therapeutic pipeline.

The role requires strong cell biology expertise, hands-on experience with primary cells, and collaboration across cross-functional teams in a fast-paced environment.