Lead Platform Engineer — AI Biology Systems

GenBio.ai, Inc.

Palo Alto, Northern (CA, KY)

Hybrid

USD 250,000 - 350,000

Full time

14 days+
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Job summary

GenBio AI, Inc. in Palo Alto is seeking an experienced Staff to Principal-level Software Engineer to build the user-facing platform that enables computational biologists, experimental scientists, and pharmaceutical researchers to interact with a growing Virtual Cell world.

This senior IC will shape architecture and drive end-to-end platform development. You will partner with AI researchers, product teams, and biologists to translate foundational models into reliable, accessible scientific

Qualifications

  • Extensive industry experience (typically 8+ years) operating at a Staff or Principal level, with a proven track record of building production web services, scalable APIs, and complex distributed backend systems.
  • Exceptional software engineering fundamentals, demonstrating a mastery of clean architecture, modular system design, and the ability to write highly maintainable, performant code.
  • Deep, hands-on experience integrating large-scale AI, LLMs, or machine learning inference systems into highly available production environments.
  • Proven ability to solve challenging, ambiguous systems problems from the ground up, moving from concept to scalable execution.
  • Outstanding cross-functional communication and leadership skills, with the ability to bridge the gap between deeply technical engineering teams, AI researchers, and scientific product teams.

Responsibilities

  • Act as a senior technical leader to build the software platform for programmable biology, developing production-grade backend services and APIs for our Virtual Cell products.
  • Design clean, robust interfaces that seamlessly connect frontend applications, core business logic, massive biological databases, and state-of-the-art AI inference engines.
  • Architect and develop highly scalable systems for complex biological simulations, experiment management, workflow orchestration, and the processing of multimodal biological data.
  • Drive continuous improvements in platform performance and reliability through highly efficient architecture design, strategic caching, asynchronous execution, and optimized distributed infrastructure.
  • Collaborate closely with AI researchers to translate cutting-edge foundation models into reliable, user-facing scientific products that enable virtual perturbations and hypothesis generation.
  • Work cross-functionally across frontend, backend, infrastructure, and machine learning teams to deliver deeply intuitive computational experiences for biologists, experimental scientists, and pharmaceutical researchers.

Skills

Staff/Principal level experience
Web services & APIs
Distributed backend systems
AI integration
Cross-functional leadership
Clean architecture

Job description

GenBio AI, Inc. in Palo Alto is seeking an experienced Staff to Principal-level Software Engineer to build the user-facing platform that enables computational biologists, experimental scientists, and pharmaceutical researchers to interact with a growing Virtual Cell world.

This senior IC will shape architecture and drive end-to-end platform development. You will partner with AI researchers, product teams, and biologists to translate foundational models into reliable, accessible scientific

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