Senior Immunology Scientist - In Vivo & In Vitro

Seismic Therapeutic; Watertown (MA); On-site; USD 95,000 - 120,000; Full time

Job summary

SEISMIC THERAPEUTIC in Watertown, MA seeks a Senior Associate Scientist for In Vivo Pharmacology to support autoimmune disease programs. The role emphasizes hands-on in vivo/in vitro work, immune cell modulation, and pharmacodynamic assessment of novel therapeutics.

You will schedule and execute preclinical studies, coordinate logistics, and collaborate with project leads in a fast-paced, team-oriented environment. A strong background in biology and animal welfare is required.

Qualifications

• BS or MS with hands-on in vivo research experience and independent study execution.
• Proficiency with in vivo procedures including mouse handling and dosing.
• Experience with autoimmune or inflammatory disease models is a plus.
• Proficiency with GraphPad Prism and Excel for data analysis.
• Strong attention to detail and commitment to high-quality data and reproducibility.
• Commitment to IACUC and animal welfare policies.

Responsibilities

• Execute in vivo and in vitro studies supporting autoimmune disease programs and evaluate immune modulation and pharmacodynamics.
• Perform hands-on in vivo procedures including dosing (RO, IP, IV, SC), survival bleedings, tissue collection and necropsy.
• Collaborate with research leads on study design, endpoints, data interpretation and troubleshooting.
• Coordinate study logistics including dosing schedules, sample collection and reagent prep.
• Analyze, visualize and summarize study data; maintain records of data, samples and protocols.
• Ensure all work complies with IACUC-approved protocols and biosafety policies.

Skills

In vivo procedures

Mouse handling

Flow cytometry (preferred)

ELISA (preferred)

GraphPad Prism

Excel

Attention to detail

Animal welfare compliance

Education

BS or MS in Biology/Immunology/Pharmacology

Job description

SEISMIC THERAPEUTIC in Watertown, MA seeks a Senior Associate Scientist for In Vivo Pharmacology to support autoimmune disease programs. The role emphasizes hands-on in vivo/in vitro work, immune cell modulation, and pharmacodynamic assessment of novel therapeutics.

You will schedule and execute preclinical studies, coordinate logistics, and collaborate with project leads in a fast-paced, team-oriented environment. A strong background in biology and animal welfare is required.