Senior PCB Systems Engineer — High-Speed Mixed-Signal HW

Flagship Pioneering; Cambridge (MA); On-site; USD 108,000 - 176,000; Full time

Job summary

Tilde Bio, Inc. is assembling a multidisciplinary engineering team to design, validate, and deliver next-generation PCB solutions for a proteomics platform.

The Senior Electrical Engineer will own complex, multilayer PCBs, ensure high-speed interfaces, and drive hardware reliability from concept through production. Ideal candidates bring strong signal integrity, power integrity, and EMI/EMC expertise, plus hands-on lab experience with test equipment and collaboration across firmware, mechanical,

Qualifications

• Requires a degree in Electrical Engineering or related field.
• 7+ years of PCB design and hardware development experience.
• Experience with multilayer PCB design for mixed-signal or high-speed systems.
• Experience with high-speed interfaces (USB, Ethernet, PCIe, DDR, SPI, I2C).
• Deep understanding of signal integrity, power integrity, EMI/EMC mitigation.
• Hands-on board bring-up, debugging, and lab instrumentation.
• Experience taking products from prototype through manufacturing.

Responsibilities

• Lead the design and development of complex, multilayer PCBs for advanced instrumentation systems.
• Architect mixed-signal, high-speed, and low-noise circuit designs including analog front ends, power management, data acquisition, and embedded processing systems.
• Collaborate with SW and HW engineers as well as external vendors to ensure seamless hardware–software integration and instrument development.
• Develop and maintain comprehensive documentation including schematics, layout files, validation reports, and specifications.
• Drive design reviews, design for manufacturability (DFM), and design for testability (DFT) best practices.
• Contribute to intellectual property generation and technical strategy discussions.

Skills

PCB design

mixed-signal design

high-speed design

signal integrity

power integrity

lab debugging

communication skills

Education

B.S./M.S./Ph.D. in Electrical Engineering

Tools

HDI design

FPGA

Embedded processors

Oscilloscope/Spectrum analyzer

Job description

Tilde Bio, Inc. is assembling a multidisciplinary engineering team to design, validate, and deliver next-generation PCB solutions for a proteomics platform.

The Senior Electrical Engineer will own complex, multilayer PCBs, ensure high-speed interfaces, and drive hardware reliability from concept through production. Ideal candidates bring strong signal integrity, power integrity, and EMI/EMC expertise, plus hands-on lab experience with test equipment and collaboration across firmware, mechanical,