Senior Molecular Biology Scientist - Strain Engineering

Checkerspot, Inc.; Alameda (CA); In loco; USD 80.000 - 130.000; Tempo pieno

Vantaggi offerti da questo lavoro

Competitive salary

Descrizione del lavoro

Checkerspot Biosciences is seeking a Senior Research Associate or Scientist to join the Molecular Biology group in Alameda, CA. You will design and execute molecular biology experiments to modify microbial metabolism and improve strain performance, using DNA analysis and high-throughput techniques.

Collaboration across teams and documentation for IP/regulatory filings are key aspects of the role. Ideal candidates have 3–6 years of industry experience (or advanced degrees) and a strong background

Competenze

• Bachelor's degree or Master’s degree with minimum of 3-6 years of relevant industry experience, or Ph.D. in Molecular Biology, Microbiology, Biochemistry, Genetics, or related disciplines.
• Experience with standard molecular biology/molecular genetic techniques including PCR, qRT-PCR, cloning, library screening, DNA and RNA purification
• Hands-on experience constructing, validating and screening engineered bacterial, fungal or microalgal strains or mammalian cell lines for producing novel molecules and improving productivity and yield; experience with developing new, robust screening tools and transformation strategies is desirable.
• Demonstrated ability to plan experiments, troubleshoot technical problems, interpret experimental results, and determine appropriate next steps, with increasing independence based on experience and role level.
• Strong understanding of basic biochemistry principles, metabolism and strain engineering
• Ability to manage large datasets and draw conclusions from them
• Excellent written, oral communication and presentation skills
• Experience working in cross-functional teams and communicating scientific results to technical collaborators and management
• Committed to safety in a laboratory environment
• Must be legally authorized to work in the United States on a full-time basis without company sponsorship

Mansioni

• Design, execute, and troubleshoot experiments to alter metabolism of microbial strains and improve productivity, yield, and production of novel molecules.
• Utilize bioinformatics and DNA sequence analysis to support construct design and validate engineered strains.
• Analyze results using statistical tools, document experiments in Benchling, present to collaborators and design follow-up experiments.
• Develop and refine genetic tools by identifying bottlenecks and bringing in new techniques from literature.
• Collaborate with Strain Improvement, Bioinformatics, Fermentation Development and Analytical teams to assess impacts on performance metrics.
• Use automated liquid handling robots for high throughput tasks.
• Assist in preparing technical documentation for IP and regulatory filings.

Conoscenze

Molecular biology

Data analysis

Troubleshooting

Experimental design

Communication

Team collaboration

Lab safety

Formazione

Bachelor's degree

Master’s degree

PhD in relevant field

Strumenti

PCR

qRT-PCR

DNA sequencing

Cloning

Benchling

Descrizione del lavoro

Checkerspot Biosciences is seeking a Senior Research Associate or Scientist to join the Molecular Biology group in Alameda, CA. You will design and execute molecular biology experiments to modify microbial metabolism and improve strain performance, using DNA analysis and high-throughput techniques.

Collaboration across teams and documentation for IP/regulatory filings are key aspects of the role. Ideal candidates have 3–6 years of industry experience (or advanced degrees) and a strong background