Senior Modeling & Simulation Leader - Drug Development

MFS Investments; Boston (MA); Hybrid; USD 168,000 - 252,000; Full time

Benefits offered by this job

Annual bonus

Equity awards

Job summary

Vertex seeks a Modeling & Simulations Associate Director to lead M&S strategies in cross-functional drug development teams. You will design and execute state-of-the-art PK/PD modeling, population PK/PD analyses and clinical trial simulations to inform critical development decisions.

The role requires a PhD or equivalent in pharmacometrics or quantitative science with 6+ years (PhD) or 10+ years (MS) of industry experience, plus strong collaboration, leadership, and communication skills in a

Qualifications

• PhD with 6+ years or MS with 10+ years in pharmacometrics modeling.
• Expert in PK/PD modeling and population PK/PD analyses.
• Experience with model-based trial simulations and dose selection.
• Strong collaboration and communication in cross-functional teams.

Responsibilities

• Lead M&S plans and analyses in cross-functional teams.
• Perform mechanism-based PK/PD analyses and trial simulations.
• Support training and adoption of new M&S tools.
• Contribute to critical development decisions through modeling insights.

Skills

PK/PD modeling

Population PK

Clinical trial simulations

Disease progression

NonMem & PsN

Leadership

Communication skills

Clinical development

Education

Pharmacometrics degree

Tools

NonMem

PsN

R

Phoenix

Job description

Vertex seeks a Modeling & Simulations Associate Director to lead M&S strategies in cross-functional drug development teams. You will design and execute state-of-the-art PK/PD modeling, population PK/PD analyses and clinical trial simulations to inform critical development decisions.

The role requires a PhD or equivalent in pharmacometrics or quantitative science with 6+ years (PhD) or 10+ years (MS) of industry experience, plus strong collaboration, leadership, and communication skills in a