Senior Metabolomics/Lipidomics Associate (LC-MS)

UMass Chan Medical School; Worcester (MA); On-site; USD 70,000 - 110,000; Full time

Job summary

UMass Chan Medical School is seeking a motivated individual to support metabolism-based research using high-resolution LC-MS. You will lead projects, prepare samples, optimize workflows, and collaborate with researchers to advance metabolomics and lipidomics studies.

The role involves data analysis, report generation, and contributing to grant writing and manuscripts. You will operate and troubleshoot multiple mass spectrometers, develop new methods, and supervise junior staff while maintaining

Qualifications

• 5+ years of relevant research with a bachelor’s degree or 3+ years with a related master's or PhD.
• Experience analyzing small molecules using chromatography and mass spectrometry.
• Familiarity with high-resolution accurate-mass spectrometers (e.g. Orbitraps).
• Ability to work collaboratively with customer service-oriented approach.
• Recent bench work experience is required.
• Ability to prepare research reports and communicate findings clearly.
• Good verbal and written communication skills.
• Demonstrated ability to understand scientific concepts and experimental design.

Responsibilities

• Serve as project lead on multiple projects with different collaborators.
• Assist with weekly cleaning and calibration of LCMS instrumentation and data quality checks.
• Prepare samples for metabolomics and lipidomics experiments.
• Optimize extraction protocols for robust data.
• Perform LC/MS/MS experiments for targeted and untargeted analyses.
• Analyze data using software such as TraceFinder, Compound Discoverer and LipidSearch.
• Consult with researchers on experimental design and data interpretation.
• Produce reports and share findings with collaborators.
• Participate in grant writing and manuscript preparation.
• Present data at group meetings and scientific conferences as needed.
• Operate, maintain, and troubleshoot mass spectrometers.
• Develop new metabolomics/lipidomics methods and workflows.
• Maintain detailed records and adhere to SOPs.
• Supervise and train new laboratory personnel and junior members.
• Serve as EHS contact and uphold safety standards.

Skills

5+ years of relevant research

Mass spectrometry analysis

High-resolution MS familiarity

Collaborative mindset

Recent bench work experience

Research reporting ability

Verbal and written communication

Understanding scientific theory

Education

Bachelor's degree in biological sciences / biochemistry / analytical chemistry

Advanced degree (MS/PhD) preferred

Job description

UMass Chan Medical School is seeking a motivated individual to support metabolism-based research using high-resolution LC-MS. You will lead projects, prepare samples, optimize workflows, and collaborate with researchers to advance metabolomics and lipidomics studies.

The role involves data analysis, report generation, and contributing to grant writing and manuscripts. You will operate and troubleshoot multiple mass spectrometers, develop new methods, and supervise junior staff while maintaining