Senior Metabolomics Associate – LC-MS & Lipidomics

University of Massachusetts Medical School; Bloomingdale (MA); On-site; USD 90,000 - 130,000; Full time

Job summary

University of Massachusetts Medical School's UMass Chan Metabolomics Core Facility is seeking a motivated individual to support metabolism-based research using high-resolution LC-MS. The role involves bench work, method development, and collaboration with researchers to advance LC/MS-based metabolomics and lipidomics projects.

You will lead projects, optimize sample preparation, perform LC/MS/MS analyses, and help with data interpretation, reporting, and manuscript preparation.

Qualifications

• 5+ years of relevant research experience with a bachelor’s degree in biological science/biochemistry/(analytical) chemistry or 3+ years relevant research experience with a related master's degree or Ph.D.
• Experience analyzing small molecules using chromatography and mass spectrometry
• Familiarity with high-resolution accurate-mass spectrometers (e.g. Orbitraps)
• Willingness to work in a collaborative environment with an outfacing customer service acumen
• Recent bench work experience required
• Ability to prepare research reports
• Good verbal and written communication skills
• Demonstrated ability to understanding scientific, experimental and or research theory

Responsibilities

• Serve as project lead on multiple collaborations
• Assist with weekly cleaning and calibration of LCMS instrumentation and data quality checks
• Prepare samples for metabolomics/ lipidomics experiments
• Optimize extraction protocols
• Assist researchers with metabolite extractions
• Perform LC/MS/MS experiments for targeted and untargeted metabolomics and lipidomics
• Perform data analysis using software such as TraceFinder, Compound Discoverer and LipidSearch
• Consult with researchers on experimental design and data interpretation
• Produce reports and share them with collaborators
• Participate in grant writing and manuscript preparation
• Present data at group meetings, may attend scientific conferences
• Operate, maintain, and troubleshoot a variety of mass spectrometers
• Develop new metabolomics/lipidomics methods and workflows when needed
• Assist with general laboratory tasks as needed
• Maintain detailed records and adhere to SOPs
• Supervise and train new laboratory personnel and junior members of the laboratory
• Serve as EHS contact and monitor and enforce laboratory safety standards
• Perform other duties as assigned

Skills

Small molecule analysis

Verbal and written communication

Recent bench work experience

Research report preparation

Education

Bachelor’s degree in biological sciences/biochemistry/analytical chemistry

Master’s degree or Ph.D. in a related field

Tools

TraceFinder

Compound Discoverer

LipidSearch

LC/MS instrumentation

Job description

University of Massachusetts Medical School's UMass Chan Metabolomics Core Facility is seeking a motivated individual to support metabolism-based research using high-resolution LC-MS. The role involves bench work, method development, and collaboration with researchers to advance LC/MS-based metabolomics and lipidomics projects.

You will lead projects, optimize sample preparation, perform LC/MS/MS analyses, and help with data interpretation, reporting, and manuscript preparation.