Senior Mass Spec Bioanalysis Scientist

BioSpace; Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Job summary

Regeneron in Tarrytown, NY is seeking a Senior Associate Scientist in the Assay Development Group to develop and execute mass spectrometry–based methods for biologics and related modalities. You will generate high-quality data and communicate findings that advance programs.

Responsibilities include optimizing MS assays, performing HPLC/UHPLC analyses, ensuring GLP-compliant documentation, and collaborating with Bioanalytical Sciences, Regeneron, and CROs to support programs.

Qualifications

• Bachelor's or Master's degree in Biophysics, Biochemistry, Chemistry, Engineering or related field.
• Ability to independently design experiments, analyze data, and communicate findings to technical audiences.
• Hands-on experience operating HPLC/UHPLC and mass spectrometry instrumentation (QQQ, Q-TOF, Orbitrap).
• Strong initiative, organization, and ability to prioritize multiple projects with minimal supervision.

Responsibilities

• Optimize, troubleshoot, and execute quantitative mass spectrometry assays for biomarkers and biologics.
• Perform hands-on laboratory work using HPLC/UHPLC, mass spectrometry, KingFisher-based purification or extraction, and related quantitation/characterization techniques.
• Analyze and interpret complex datasets; maintain electronic laboratory notebook records; and present findings clearly to technical and cross-functional audiences.
• Manage multiple assays and projects concurrently and evaluate emerging technologies and assay formats.
• Maintain GLP-compliant laboratory practices and documentation for assay validations in accordance with FDA regulations and SOPs.
• Collaborate within Bioanalytical Sciences, across Regeneron, and with CROs to troubleshoot challenges and support program execution.

Skills

Mass spectrometry

HPLC/UHPLC

Data analysis

GLP compliance

Cross-functional collaboration

Education

Bachelor's or Master's in Biophysics, Biochemistry, Chemistry, Engineering

Tools

KingFisher

Job description

Regeneron in Tarrytown, NY is seeking a Senior Associate Scientist in the Assay Development Group to develop and execute mass spectrometry–based methods for biologics and related modalities. You will generate high-quality data and communicate findings that advance programs.

Responsibilities include optimizing MS assays, performing HPLC/UHPLC analyses, ensuring GLP-compliant documentation, and collaborating with Bioanalytical Sciences, Regeneron, and CROs to support programs.