Senior Manager, Research Informatics

Revolution Medicines; San Francisco (CA); On-site; USD 164,000 - 205,000; Full time

Job summary

Revolution Medicines in Redwood City, CA seeks a Senior Manager, Research Informatics to lead strategy, development, and governance of research informatics capabilities for Discovery Research.

You will partner with scientists, computational teams, and IT to standardize workflows, implement enterprise platforms like Genedata Screener and Benchling, and enable scalable data management and AI-enabled discovery.

Qualifications

• Bachelor’s degree in a scientific, computational, or related field; advanced degree preferred.
• 7–9 years leading research informatics or lab data initiatives in biotech/pharma settings.
• Experience with assay management platforms (Genedata Screener, IDBS ActivityBase, Revvity Signals).
• Strong understanding of discovery workflows, data lifecycle management, and enterprise informatics ecosystems.
• Ability to translate scientific and business needs into scalable technology roadmaps.
• Experience leading cross-functional programs with scientists, software engineers, and vendors.
• Working knowledge of SQL, Python, data standards, and modern integration approaches.
• Excellent communication and executive presentation skills.

Responsibilities

• Develop and execute the research informatics strategy to support scalable workflows across Discovery Research.
• Partner with scientific, computational, and technology teams to align priorities with informatics capabilities.
• Lead design, governance, and lifecycle management of data models, templates, workflows, and platforms (Genedata Screener, Benchling).
• Automate data capture, assay analysis, reporting, and integrations to improve efficiency and data integrity.
• Establish standards for data management, metadata, workflow design, and application lifecycle management.
• Build partnerships with scientists, IT, vendors, and collaborators to deliver informatics solutions.
• Drive user adoption through training, change management, and stakeholder engagement.
• Assess emerging technologies and define strategies for AI-enabled discovery.

Skills

Leadership

Communication

Strategic thinking

Cross-functional collaboration

Project management

Education

Bachelor’s degree in scientific/computational field

Advanced degree preferred

Tools

Genedata Screener

Benchling

IDBS ActivityBase

Revvity Signals

Genedata Expressionist

APIs / data pipelines

Job description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

We are seeking a Senior Manager, Research Informatics to lead the strategy, development, and evolution of research informatics capabilities that accelerate Discovery Research. In this role, you will partner closely with scientific teams, computational scientists, and technology teams to define and deliver scalable digital solutions that transform how scientific data is captured, managed, analyzed, and leveraged across the research organization.

You will lead initiatives to modernize research workflows by driving standardization, automation, expanding the adoption of enterprise platforms over standalone applications, and seamless integration across the research informatics ecosystem. By establishing scalable data frameworks, governance, and best practices, you will enable high-quality, traceable, and reusable scientific data that supports operational excellence, advanced analytics, and AI-enabled discovery. In this role you will be responsible for:

• Develop and execute the research informatics strategy to support scalable, efficient, high-quality workflows across Discovery Research.
• Partner with scientific, computational, and technology teams to align research priorities with informatics capabilities and technology roadmaps.
• Lead the design, governance, and lifecycle management of research data models, templates, workflows, and enterprise platforms, including Genedata Screener and Benchling.
• Automate and optimize data capture, assay analysis, reporting, and system integrations to improve efficiency, reproducibility, and data integrity.
• Establish standards and best practices for data management, metadata, workflow design, system configuration, and application lifecycle management.
• Build partnerships with scientists, computational teams, IT, vendors, and external collaborators to deliver high-impact informatics solutions.
• Prioritize application enhancements, support needs, and operational improvements to maintain strong service levels and user satisfaction.
• Drive user adoption through clear communication, training, change management, and stakeholder engagement.
• Assess emerging technologies, including AI-enabled platforms and advanced analytics, and define implementation strategies that improve scientific productivity.

Required Skills, Experience and Education

• Bachelor’s degree in a scientific, computational, or related field; advanced degree preferred.
• 7 – 9 years of experience leading research informatics, scientific applications, or laboratory information management initiatives in biotech, pharmaceutical, or research settings.
• Experience with Assay Management platforms such as Genedata Screener, IDBS ActivityBase or Revvity Signals.
• Strong understanding of discovery research workflows, scientific data management, assay informatics, laboratory operations, and research data lifecycle management.
• Experience implementing, optimizing, and governing enterprise scientific platforms and informatics ecosystems.
• Proven ability to translate scientific and business needs into scalable technology solutions and long-term roadmaps.
• Experience leading cross-functional programs with scientists, software engineers, and external vendors.
• Working knowledge of workflow automation, systems integration, data standards, SQL, Python, and modern data integration approaches.
• Excellent communication, leadership, and executive presentation skills, with the ability to influence technical and scientific stakeholders.
• Demonstrated people leadership, coaching, and organizational development experience.

Preferred Skills

• Experience with Genedata Screener, Genedata Expressionist, Benchling, D360, Mosaic, or similar scientific informatics platforms.
• Experience supporting high-throughput screening, assay development, translational research, and discovery research teams.
• Knowledge of APIs, data pipelines, cloud-based research platforms, and enterprise integration architectures.
• Experience establishing research data governance, FAIR data principles, metadata standards, and reusable data frameworks.
• Experience developing informatics capabilities that support machine learning, AI-enabled workflows, or advanced analytics.
• Familiarity with resource planning, roadmap planning, vendor management, software licensing, and budgets.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range

$164,000 - $205,000 USD

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [e-mail].