Senior Manager, Drug Substance Manufacturing Programs

Amgen Inc.; Thousand Oaks (CA); On-site; USD 121,000 - 163,000; Full time

Job summary

Amgen Inc. in Thousand Oaks, CA seeks a Manager of Manufacturing to lead a team responsible for upstream drug substance operations, technology transfer, and continuous improvement initiatives.

You will guide project delivery, ensure GMP compliance, and partner with cross-functional groups to optimize processes and equipment. The role demands strong leadership, deep knowledge of manufacturing science, and hands-on collaboration on validation, change control, and operational readiness for new

Qualifications

• Advanced degree and leadership experience in manufacturing operations.
• Experience managing people, projects, and cross-functional teams.
• Experience with GMP documentation and validation processes.

Responsibilities

• Lead a team of manufacturing specialists in upstream operations.
• Drive continual improvement and lead technology readiness.
• Oversee CAPA, deviation investigations, and change control.
• Draft GMP documents (SOPs, forms) and user requirements for new tech.

Skills

People leadership

Project management

GMP knowledge

Data analysis

Education

Bachelor's degree in Engineering or Life Sciences

Job description

Amgen Inc. in Thousand Oaks, CA seeks a Manager of Manufacturing to lead a team responsible for upstream drug substance operations, technology transfer, and continuous improvement initiatives.

You will guide project delivery, ensure GMP compliance, and partner with cross-functional groups to optimize processes and equipment. The role demands strong leadership, deep knowledge of manufacturing science, and hands-on collaboration on validation, change control, and operational readiness for new