Senior LC-MS Protein Analytics Scientist

KBI Biopharma, Inc.; Colorado; On-site; USD 118,000 - 148,000; Full time

Job summary

KBI Biopharma, Inc. in Boulder, CO is seeking a Senior Analytical Scientist to join the Analytical and Formulation Sciences team. You will serve as an SME for LC-MS-based protein analytics, guiding analytical testing across development to commercialization and collaborating with process development, characterization, and regulatory teams.

The role requires a PhD with multiple years in biopharma analytics, strong communication, and the ability to mentor junior staff in a fast-paced environment.

Qualifications

• Ph.D. in Biophysics, Biochemistry, Analytical Chemistry or Biochemical Engineering with 4+ years experience for Senior or 6+ years for Principal.
• Able to adapt to change and perform varied tasks as needed.
• Adhere to safety requirements and ensure compliance.
• Strong understanding of protein structure, aggregation, and higher-order structure analysis.
• Excellent communication skills and ability to present complex data to diverse audiences.
• Proficient in scientific software and data analysis tools.
• Able to work independently and collaboratively in a fast-paced environment.
• Experience with fermentation development for protein expression and downstream operations (chromatography, TFF, refold, conjugation) is a plus.

Responsibilities

• Design and execute analytical experiments in support of biotherapeutics Process Development.
• Demonstrate expertise in LC-MS, HPLC/UPLC, and other analytical techniques.
• Design and implement analytical strategies to support product development and regulatory submissions.
• Generate high-quality documentation suitable for publication and regulatory review.
• Act as SME on client programs, providing technical guidance and representing KBI in client interactions.
• Mentor and train junior scientists and associates.
• Perform peer reviews of data and reports related to method development, qualification, and validation.
• Manage timelines and resources to meet project milestones.
• Advise leadership on program status and technical challenges.
• Contribute to continuous improvement initiatives within the AFS team.

Skills

LC-MS

HPLC/UPLC

Analytical chemistry

Data analysis

Communication

Independence

Education

PhD in Biophysics

PhD in Biochemistry

PhD in Analytical Chemistry

PhD in Biochemical Engineering

Tools

Mass spectrometry software

Data analysis tools

Job description

KBI Biopharma, Inc. in Boulder, CO is seeking a Senior Analytical Scientist to join the Analytical and Formulation Sciences team. You will serve as an SME for LC-MS-based protein analytics, guiding analytical testing across development to commercialization and collaborating with process development, characterization, and regulatory teams.

The role requires a PhD with multiple years in biopharma analytics, strong communication, and the ability to mentor junior staff in a fast-paced environment.