Senior Global Oncology Trial Leader

MacroGenics, Inc.; Rockville (MD); On-site; USD 150,000 - 229,000; Full time

Benefits offered by this job

Discretionary bonus

Equity incentives

Medical/dental/vision/prescription

401(k) with employer match

Employee Stock Purchase Plan (ESPP)

Paid time off

Paid parental leave

Disability benefits

Job summary

MacroGenics, Inc. is seeking a Sr. Global Trial Manager to lead cross-functional teams through all phases of global clinical trials in oncology.

You will manage timelines, budgets, sites, and vendors, ensuring quality and regulatory compliance. You will lead Go Teams and coordinate internal and CRO partners to drive program objectives. Qualified candidates will have a Bachelor’s degree in a scientific discipline, 7+ years in clinical operations, and 5+ years in oncology trial management, with

Qualifications

• Bachelor’s degree in a relevant scientific discipline.
• Minimum of seven years of clinical operations experience in pharma/biotech or CRO.
• At least 5 years of trial management experience in oncology.
• Experience in managing global trials.

Responsibilities

• Global Clinical Trial Management – oversee trials within study budgets, timelines and quality standards.
• Go Team Lead: oversee timelines, cross-functional alignment and risk mitigation.
• Clinical Trial Planning – provide operational input before trials start, including protocol development and site selection.
• Monitoring Activities – oversee CRO and site monitoring to ensure GCP compliance and data integrity.
• Site Management – manage communication with sites, budgets and invoices.
• Vendor Oversight – select CROs and manage third-party vendors.
• Internal/External Meetings – run study team and investigator meetings.
• Data Listing Review – oversee data listings and corrective actions.
• Trial Master File – ensure TMF readiness and regulatory compliance.
• Ancillary Supplies – coordinate materials and budget.
• Study Management Tools – ensure use of appropriate tools by teams and sites.
• Clinical Operations Responsibilities – contribute to SOPs and process improvements.

Skills

GCP knowledge

Budget management

Cross-functional leadership

Vendor management

Site management

Regulatory compliance

Trial planning

Communication

Travel to sites

Global trial management

Education

Bachelor’s degree in a relevant scientific discipline

Tools

CTMS

IXRS

Job description

MacroGenics, Inc. is seeking a Sr. Global Trial Manager to lead cross-functional teams through all phases of global clinical trials in oncology.

You will manage timelines, budgets, sites, and vendors, ensuring quality and regulatory compliance. You will lead Go Teams and coordinate internal and CRO partners to drive program objectives. Qualified candidates will have a Bachelor’s degree in a scientific discipline, 7+ years in clinical operations, and 5+ years in oncology trial management, with