Global Early-Stage Oncology Clinical Trial Manager

Repertoire Immune Medicines, Inc.; Cambridge (MA); On-site; USD 112,000 - 160,000; Full time

Job summary

Repertoire Immune Medicines, Inc. in Cambridge, MA is seeking a Clinical Trial Manager to provide strategic leadership and hands-on oversight of early-stage oncology trials, including first-in-human studies.

You will report to the Director of Clinical Operations and coordinate cross-functional teams, CROs, vendors, and sites to deliver trials on time and in compliance. The role requires 3+ years of trial management, strong CRO/vendor oversight, global trial experience, and expertise with

Qualifications

• Bachelor’s degree in Life Sciences or related field; 3+ years clinical trial management.
• Proven CRO and vendor management oversight.
• Ability to lead trials independently in a fast-paced team.
• Working knowledge of data management, biostatistics, and pharmacovigilance.
• Global trial experience including multi-country management.
• Thorough understanding of FDA regulations and ICH GCP.
• Proficiency with EDC, CTMS, TMF and regulatory docs.
• On-site monitoring experience preferred.
• Excellent communication and cross-functional collaboration.
• Willingness to travel up to 20%.

Responsibilities

• Manage trial timelines, budget, and SOP/ICH/GCP compliance.
• Identify risks; plan mitigation with cross-functional teams.
• Oversee CROs and vendors performance and oversight plans.
• Manage trial budgets, invoices, and expense tracking.
• Monitor enrollment, data review, sample collection, timelines.
• Guide sites to ensure protocol adherence.
• Develop and review trial documents (protocols, ICFs, CRFs, etc.).
• Ensure TMF completeness and inspection readiness.
• Support SOPs and departmental processes.

Job description

Repertoire Immune Medicines, Inc. in Cambridge, MA is seeking a Clinical Trial Manager to provide strategic leadership and hands-on oversight of early-stage oncology trials, including first-in-human studies.

You will report to the Director of Clinical Operations and coordinate cross-functional teams, CROs, vendors, and sites to deliver trials on time and in compliance. The role requires 3+ years of trial management, strong CRO/vendor oversight, global trial experience, and expertise with