Senior Global Clinical Trial Leader - Early Phase

Orro; Cambridge (MA); On-site; USD 163,000 - 187,000; Full time

Benefits offered by this job

Equity-based compensation

Medical, dental, vision

401(k)

Life insurance

Dependent care FSA

Parking

Job summary

Korro seeks a senior clinical operations leader to drive early phase global trials in rare diseases. You will oversee CROs, study design, budgets, and timelines, collaborating with cross-functional teams to achieve program milestones.

The role requires 8+ years in clinical development, strong regulatory knowledge, and a track record delivering FIH studies. Travel up to 25% may be required as programs progress. Competitive compensation, including equity and comprehensive benefits, is offered.

Qualifications

• 8+ years in clinical development and operations leadership.
• Experience in rare diseases and early-phase studies.
• Strong cross-functional leadership.
• Deep regulatory knowledge and experience with inspections.
• Excellent communicator and strategic thinker.

Responsibilities

• Plan, drive and oversee multi-center global clinical trials in compliance with GCPs and SOPs.
• Drive implementation of clinical operational strategy for successful delivery of studies.
• Oversee CROs and vendors, including budgets and timelines; develop contingency plans.
• Coordinate and lead study team meetings; update Program Team on timelines and milestones.
• Review and write study documents: protocols, ICFs, CRFs; contribute to site selection and patient accrual tracking.
• Oversee TMF management and ensure data integrity and regulatory readiness.
• Limited travel (<25%) to field sites to supervise and monitor studies.

Skills

Cross-functional leadership

Global clinical operations

ICH GCP knowledge

Strategic thinking

Education

Bachelor’s Degree

Advanced degree desirable

Job description

Korro seeks a senior clinical operations leader to drive early phase global trials in rare diseases. You will oversee CROs, study design, budgets, and timelines, collaborating with cross-functional teams to achieve program milestones.

The role requires 8+ years in clinical development, strong regulatory knowledge, and a track record delivering FIH studies. Travel up to 25% may be required as programs progress. Competitive compensation, including equity and comprehensive benefits, is offered.