Senior Finance Partner, Clinical Development

Isomorphic Labs; Cambridge (MA); Hybrid; USD 150,000 - 230,000; Full time

Job summary

Isomorphic Labs is seeking a Senior Finance Business Partner (Clinical) to act as the financial partner for the Clinical Development team in Cambridge, MA. You will lead budgeting, forecasting, and vendor management, ensuring robust financial planning for clinical programs.

You will collaborate closely with Clinical Operations, Procurement, and site leadership to drive efficient processes and strategic decision-making, advancing our medicines toward clinical use.

Qualifications

• Clinical Finance Expertise: direct experience managing clinical development finances and FP&A within biotech or pharma.
• Education & Analytical Skills: degree in finance, accounting, economics, or other quantitative field.
• Communication & Rigor: clear executive-level communicator for technical and non-technical audiences.
• Teamwork and collaboration: proven track record in business partnering and stakeholder management.
• AI to drive efficiency: experience using LLMs or AI to improve efficiency.

Responsibilities

• Serve as the primary finance partner for the Clinical Development team and provide strategic thought partnership.
• Lead end‑to‑end budgeting, forecasting, and resource planning for clinical studies with bottoms‑up models.
• Partner with Clinical Operations and Procurement during vendor processes to evaluate budgets and support onboarding and P2P.
• Deliver regular variance analysis and enhance financial reporting and workflows to support portfolio growth.
• Act as Cambridge site finance lead and partner with site leadership.

Skills

Collaborative Partner

Proactive Problem Solver

Detail-Oriented

Independent Growth-Oriented

AI to drive efficiency

Education

Finance/Accounting/Economics degree

Job description

Senior Finance Business Partner (Clinical), Cambridge, MA

Cambridge, MA

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.

About Iso

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

Your impact

As our Senior Finance Business Partner (Clinical Development), you will serve as the dedicated financial strategic partner to our growing Clinical Development team. You will be a critical contributor to the success of this team and will be responsible for financial management of all clinical-related work.

This is a new role supporting our team based in Cambridge, MA. You will have the opportunity to bring financial thought leadership and rigor to key stakeholders as Iso progresses more medicines into the clinic as we march towards our mission to Solve All Disease.

About you

• Collaborative Partner: Someone who builds trusting relationships, acts as a strategic thought partner and can bridge between science and finance.
• Proactive Problem Solver: A curious, resourceful mindset with the drive to resolve issues pragmatically and optimise our playbook and processes.
• Detail and Process Oriented: Highly organized and meticulous with clinical trial budgets. Capable of balancing multiple operational workflows whilst maintaining high standards.
• Independent and Growth-Oriented: A self-starter, always looking for ways to streamline processes and leverage technology to increase efficiency.

What you will do

• Business & Financial Partnering: Serve as the primary finance partner for the Clinical Development team. Provide strategic thought partnership to support delivery of clinical portfolio objectives.
• Budgeting and Forecasting: You will guide end-to-end clinical budgeting, forecasting, and resource planning. You will build and maintain bottoms-up financial models for clinical studies (e.g. tracking site activations, patient enrolment, pass-through costs etc)
• Vendor Oversight & Advisory: Partner with Clinical Operations and Procurement during RFP processes to evaluate, benchmark, and negotiate budgets with clinical vendors. Support vendor onboarding, invoice review/approval, P2P processes and troubleshooting.
• Reporting & Process Improvement: Deliver regular variance analysis and continuously enhance financial reporting and workflows to support portfolio growth. Develop robust and efficient accruals processes.
• Cambridge Finance Lead: As our first finance hire in Cambridge, MA, you will act as the Cambridge site finance lead and partner closely with the site leadership team.

Skills and qualifications

• Clinical Finance Expertise: Direct experience managing clinical development finances (CROs, sites) and FP&A/partnering within biotech, pharma, or life sciences. Deep experience in financial analysis including building and maintaining robust patient-driven financial models.
• Education & Analytical Skills: Degree in Finance, Accounting, Economics, or other quantitative field.
• Communication & Rigor: Clear executive-level communicator for both technical and non-technical audiences. Strong attention to detail and ability to manage competing priorities in a fast-paced environment.
• Teamwork and collaboration: Proven track record in business partnering and excellence in stakeholder management.
• AI to drive efficiency: Experience in utilizing LLMs and other AI to drive efficiency

Nice to have:

• Professional accounting qualification (e.g., ACA, ACCA, CIMA, CPA, or equivalent).
• Experience managing financial systems (e.g. ERP, procurement).

Culture and values

We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.

Thoughtful
Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.

Brave
Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.

Determined
Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.

Together
Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.

Creating an extraordinary company

We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.

It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.

Please note that when you submit an application, your data will be processed in line with our privacy policy .

Interested in building your career at Isomorphic Labs? Get future opportunities sent straight to your email.

Accepted file types: pdf, doc, docx, txt, rtf

Enter manually

Accepted file types: pdf, doc, docx, txt, rtf

As an AI-first company, we embrace tools like Gemini. However, our interview process is designed to understand your unique expertise and problem-solving skills, as well as what motivates you.Therefore, we ask that you refrain from using any AI tools, transcription services, or other assistants during your interview and assessment process, unless you've made prior arrangements with our Talent team for specific needs or accommodations. (If you require any adjustments, please discuss this with the Talent team during your initial screening call.) *

By checking this box and proceeding with your application, you confirm that you have read and agreed to these terms and will not use any AI tools or assistants during the interview and assessment process.

In which of our office locations would you prefer to be based? (Note that certain jobs may only be available in one location - please check the details before applying) * Select...

What are your salary expectations (base / total package)? Please note that this is what you would be looking for in your next role, NOT your current package.

What is your current notice period?

Where did you hear about Iso?

Press article / publication

DeepMind website

LinkedIn

Twitter

Indeed

Other job board

Search engine

Conference/event (please let us know which one below)

Alphabet Grow (current employee of GDM)

Alphabet Grow (current employee of any other Bet)

Referred by an employee at Isomorphic Labs (please let us know who below)

Other

Where did you hear about Iso? (Additional info)

Is there anything else you'd like us to know?

LinkedIn Profile

Website

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Isomorphic Labs’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.