Senior Electrical Engineer, NPI

1000 Pacific Biosciences of California, Inc.; Menlo Park (CA); On-site; USD 112,000 - 168,000; Full time

Job summary

PacBio is seeking a Senior Electrical Engineer for its Instrument Engineering team to drive NPI electrical activities from concept to manufacturing ramp. You will work on PCBAs, cable assemblies, and related hardware for DNA sequencing instruments, collaborating with design, manufacturing, QA, and suppliers.

You will design and validate production test fixtures, develop schematics/layouts, and perform hands-on PCBA bring-up and testing while contributing to DFM/DFT considerations and process

Qualifications

• Bachelor’s degree in Electrical Engineering; typically 5+ years in industry.
• Experience with PCBA design, bring-up, testing, or troubleshooting.
• Experience designing electrical test fixtures or production test equipment.
• Proficiency with schematic capture and PCB layout tools; Cadence or Altium preferred.
• Working knowledge of oscillosopes, digital multimeters, power supplies, and logic analyzers.
• Understanding of DFx/DFM principles in manufacturing.
• Experience creating and maintaining engineering docs like schematics, BOMs, test procedures, and wiring drawings.
• Strong analytical, troubleshooting, and problem‑solving skills.

Responsibilities

• Support electrical NPI activities from concept through pilot builds and production ramp.
• Collaborate with design engineers to transition PCBAs and related hardware into manufacturing.
• Design, build, validate, and document production test fixtures for subassemblies and instrument-level testing.
• Develop schematics and PCB layouts for production test fixture electronics.
• Perform PCBA bring-up, electrical testing, troubleshooting, and root-cause analysis.
• Develop and maintain production test requirements, procedures, acceptance criteria, and troubleshooting docs.
• Participate in design reviews and provide manufacturing feedback (DFM/DFT).
• Support creation and release of cables, wiring diagrams, BOMs, and assembly instructions.
• Coordinate with internal teams, contract manufacturers, and suppliers to resolve issues.

Skills

PCB design

Bring-up

Test fixtures

Schematic capture

Electrical troubleshooting

DFx/DFM

Documentation

Cross-functional collaboration

Education

Bachelor's degree in Electrical Engineering

Tools

Cadence

Altium

Oscilloscopes

Digital multimeters

Power supplies

Logic analyzers

Job description

Senior Electrical Engineer, NPI The selected candidate will join the PacBio Instrument Engineering team as an NPI Electrical Engineer. This role will focus on the introduction of printed circuit board assemblies (PCBAs), cable assemblies, and related electrical hardware for DNA sequencing instruments. The engineer will work closely with Electrical Design Engineering, Manufacturing, Quality, Supply Chain, and external manufacturing partners to support products from prototype development through pilot production and manufacturing ramp. The position combines hands‑on electrical engineering, production test development, troubleshooting, documentation, and manufacturing support.

Responsibilities

• Support electrical NPI activities from concept and prototype development through pilot builds, product transfer, and production ramp.
• Collaborate with electrical design engineers to transition PCBAs, cable assemblies, and related electrical hardware into manufacturing.
• Design, build, validate, and document electrical test fixtures for production subassemblies and instrument‑level testing.
• Develop schematics and PCB layouts for production test fixture electronics.
• Perform hands‑on PCBA bring‑up, electrical testing, troubleshooting, and root‑cause analysis.
• Develop and maintain production test requirements, test procedures, acceptance criteria, and troubleshooting documentation.
• Participate in design reviews and provide design‑for‑manufacturing and design‑for‑test feedback.
• Support the development and release of cable drawings, wiring diagrams, pinout documentation, bills of materials, and assembly instructions.
• Work with internal manufacturing teams, contract manufacturers, and suppliers to resolve electrical and test‑related issues during prototype and production builds.
• Analyze production test results, failure trends, and yield data to identify opportunities for improved product quality and manufacturing efficiency.
• Support engineering change orders and maintain product documentation in PDM and PLM systems.
• Assist with the qualification of manufacturing processes, test equipment, and electrical suppliers.
• Support the transfer of products from R&D to manufacturing, including the preparation of assembly and test methods and the training of manufacturing personnel.
• Coordinate assigned activities with cross‑functional teams to meet project schedules, technical requirements, and quality objectives.
• Communicate technical findings, risks, and recommendations clearly to engineering and project stakeholders.

Required Qualifications

• Bachelor’s degree in Electrical Engineering or a related engineering discipline. Typically requires a minimum of 5 or more years of relevant industry experience.
• Experience with PCBA design, bring‑up, testing, or troubleshooting.
• Experience designing electrical test fixtures or production test equipment.
• Proficiency with schematic capture and PCB layout tools; experience with Cadence or Altium is preferred.
• Working knowledge of common electrical laboratory equipment, including oscilloscopes, digital multimeters, power supplies, and logic analyzers.
• Understanding of electrical manufacturing processes and design‑for‑manufacturing and design‑for‑test principles.
• Experience creating and maintaining engineering documentation such as schematics, bills of materials, test procedures, cable drawings, and work instructions.
• Strong analytical, troubleshooting, and problem‑solving skills.
• Ability to manage multiple technical assignments and changing priorities in a fast‑paced product‑development environment.
• Effective written and verbal communication skills.
• Demonstrated ability to work collaboratively with multidisciplinary engineering and operations teams.

Preferred Qualifications

• Experience supporting new product introduction or manufacturing transfer of complex electrical or electromechanical products.
• Experience with PCBA contract manufacturers, cable assembly suppliers, or outsourced manufacturing partners.
• Experience developing, deploying, or supporting production test stations at a contract manufacturer.
• Hands‑on electromechanical assembly and system‑level debug experience.
• Experience with PDM or PLM systems and formal engineering change‑control processes.
• Familiarity with FPGA‑based systems, embedded electronics, or digital communication interfaces.
• Familiarity with electrical safety, EMC, product qualification, and reliability testing.
• Proficiency with Microsoft 365 applications, including Excel, Outlook, SharePoint, OneDrive, Teams, and project‑management tools.

Employment Details

This role is required to be 100% onsite. You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.

Salary Range: $112,000.00 - $168,000.00

Candidates must have current authorization to work in the United States without the need for present or future sponsorship.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

Disability Accommodation

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact us at 650-521-8000, or [e-mail] for assistance.

About Us

At PacBio, we’re all on a mission to enable the promise of genomics to better human health. It’s what fuels us every day. Our team is passionate about catalyzing scientists pursuing biological discoveries, and we’re looking for exceptional individuals like you to join us. If you’re interested at being at the intersection where health and technology come together, then consider joining our team. We look forward to meeting you.

Visit our following pages for more information on: FAQs Benefits Culture Equal Opportunity Employment.

Core Values

• BE CURIOUS. Our future depends on it.
• DELIGHT OUR CUSTOMERS. We strive to get it right every time.
• TAKE ACTION. We move fast and take calculated risks.
• EXECUTION MATTERS. Our customers rely on us.
• WORK TOGETHER. We care deeply about each other.