Senior DMPK Scientist, Radiopharmaceutical PK

Aktis Oncology; Durham (NC); On-site; USD 108,000 - 148,500; Full time

Job summary

A clinical-stage oncology company is seeking a Scientist/Senior Scientist to support miniprotein-based radioconjugate discovery programs. The ideal candidate will possess a strong foundation in ADME/PK, hands-on bioanalytical experience, and excellent collaboration skills. Responsibilities include conducting method development and pharmacokinetic studies, while contributing to cross-functional teams. This position offers the chance to advance innovative cancer therapies in a dynamic environment.

Qualifications

• Strong foundation in ADME/PK and relationship between PK and physicochemical properties.
• Hands-on experience with LC-MS/MS bioanalytical methods.
• Ability to communicate findings to cross-functional teams.

Responsibilities

• Conduct bioanalytical method development and pharmacokinetic studies.
• Serve as DMPK representative on program teams.
• Advance understanding of proteolytic stability and pharmacokinetics.

Skills

ADME/PK knowledge

Bioanalytical method development

LC-MS/MS experience

Collaboration skills

Education

BS with 5+ years of relevant experience

MS with 2-3 years of relevant experience

PhD in a relevant scientific discipline

Tools

LC-MS/MS

High-resolution mass spectrometry

Job description

A clinical-stage oncology company is seeking a Scientist/Senior Scientist to support miniprotein-based radioconjugate discovery programs. The ideal candidate will possess a strong foundation in ADME/PK, hands-on bioanalytical experience, and excellent collaboration skills. Responsibilities include conducting method development and pharmacokinetic studies, while contributing to cross-functional teams. This position offers the chance to advance innovative cancer therapies in a dynamic environment.