Senior Director, Clinical Science: Strategy & Global Trials

Celldex Therapeutics, Inc.; Hampton (NJ); On-site; USD 203,000 - 264,000; Full time

Job summary

Celldex Therapeutics, Inc. is seeking a Senior Director, Clinical Science to shape clinical development strategy and oversee study design across a portfolio of programs.

You will translate complex clinical data into actionable strategies and serve as a key partner to Clinical Science leadership to advance programs through milestones including proof-of-concept, registrational studies, and regulatory submissions.

Qualifications

• Advanced degree in scientific/healthcare field (PhD/MD/PharmD) preferred.
• 15+ years of clinical research, development, or clinical science experience in biotech/pharma.
• Proven success leading Clinical Science activities across multiple phases.
• Ability to translate complex clinical data into actionable development strategies.

Responsibilities

• Provide strategic leadership for one or more clinical development programs, aligning with corporate objectives.
• Drive integrated development strategies across studies and indications, including lifecycle management.
• Serves as the Clinical Science representative to governance committees and senior leadership.
• Influence indication prioritization, dose selection, endpoints, and regulatory submission strategy.
• Partner with Clinical Science physicians, Operations, Regulatory Affairs, and executives to define development pathways.
• Evaluate scientific and regulatory developments to identify opportunities and risks.

Skills

Strategic leadership

Clinical study design

Data interpretation

Regulatory strategy

Cross-functional collaboration

Education

Advanced degree (PhD/MD/PharmD)

Job description

Celldex Therapeutics, Inc. is seeking a Senior Director, Clinical Science to shape clinical development strategy and oversee study design across a portfolio of programs.

You will translate complex clinical data into actionable strategies and serve as a key partner to Clinical Science leadership to advance programs through milestones including proof-of-concept, registrational studies, and regulatory submissions.