Senior Director, Clinical Science: PH & Cardiovascular

Merck & Co.; Rahway (NJ); On-site; USD 250,000 - 300,000; Full time

Job summary

Merck & Co. invites an experienced Senior Director, Clinical Science, Pulmonary Hypertension and Cardiovascular to lead strategic Clinical Science across multiple studies and assets, guiding development planning and standardizing scientific practices.

You will partner with Clinical Operations, Regulatory Affairs, Biostatistics and Data Management, Drug Safety, Translational Medicine and Medical Affairs to align strategies, interpret data, and drive governance discussions with senior leadership.

Responsibilities

• Provide strategic Clinical Science leadership across the disease area, covering multiple studies and assets.
• Contribute to development opportunities, scientific considerations, portfolio risks, and data implications.
• Partner with Section Heads, Asset Leads, and cross-functional leaders to align Clinical Science activities.
• Apply expert knowledge of therapeutic focus, disease biology, treatment landscape, and meaningful endpoints to inform study planning.
• Support cross-study and cross-asset integration of scientific insights to guide development decisions.
• Lead efforts to standardize Clinical Science approaches across the disease area and deliverables.
• Promote consistency in how Clinical Science activities are conducted while allowing program-specific needs.
• Advocate for innovative approaches, including visual analytics, centralized data review, and AI-enabled workflows.
• Provide senior scientific guidance across studies to ensure high-quality and consistent Clinical Science input.
• Help ensure issues are appropriately framed for governance discussions with cross-functional partners.

Job description

Merck & Co. invites an experienced Senior Director, Clinical Science, Pulmonary Hypertension and Cardiovascular to lead strategic Clinical Science across multiple studies and assets, guiding development planning and standardizing scientific practices.

You will partner with Clinical Operations, Regulatory Affairs, Biostatistics and Data Management, Drug Safety, Translational Medicine and Medical Affairs to align strategies, interpret data, and drive governance discussions with senior leadership.