Senior Director, Clinical Pharmacology & PK Modeling

BridgeBio Pharma; Owens (OH); Hybrid; USD 265,000 - 289,000; Full time

Benefits offered by this job

Market-leading compensation

401(k) with employer match

Employee Stock Purchase Program (ESPP)

Hybrid work model

Company-paid holidays

Job summary

BridgeBio Pharma in the United States seeks a Senior Director, Clinical Pharmacology to lead clinical pharmacology and pharmacometrics strategies across diverse drug development programs, with oversight of population PK, exposure‑response, PK/PD, and PBPK models. This hybrid role involves managing external bioanalytical CROs, contributing to regulatory submissions, and communicating findings to internal and external stakeholders; requires a Ph.D.

or Pharm.D.

Qualifications

• Ph.D. or Pharm.D. in Clinical Pharmacology, Pharmaceutical Sciences, or a related discipline.
• 10+ years of relevant experience in biotech or pharmaceutical industry.
• Demonstrated track record in population PK, PK/PD, PBPK, and quantitative data analysis.

Responsibilities

• Develop and implement clinical pharmacology and pharmacometrics strategies across all stages of clinical development.
• Oversee design and application of PK/PD, population PK, and PBPK models to inform decision‑making.
• Manage external bioanalytical CROs and contribute to regulatory documents and interactions with health authorities.
• Design and oversee PK studies, protocols, and analysis plans; author reports as needed.
• Present results to internal and external stakeholders and contribute to publications and conferences.

Skills

Population PK

PK/PD

PBPK modeling

Quantitative data analysis

Regulatory strategy

Education

Ph.D. or Pharm.D. in Clinical Pharmacology

Job description

BridgeBio Pharma in the United States seeks a Senior Director, Clinical Pharmacology to lead clinical pharmacology and pharmacometrics strategies across diverse drug development programs, with oversight of population PK, exposure‑response, PK/PD, and PBPK models. This hybrid role involves managing external bioanalytical CROs, contributing to regulatory submissions, and communicating findings to internal and external stakeholders; requires a Ph.D.

or Pharm.D.