Senior Data Transformation Leader - AI-Ready Clinical Data

Johnson & Johnson Co.; Cambridge (MA); On-site; USD 137,000 - 236,000; Full time

Job summary

Johnson & Johnson Innovative Medicine is hiring a Senior Manager, Data Transformation to join the DDSAI team with locations in Cambridge, MA or other U.S. sites. No remote option. The role leads end-to-end data product development for AI-ready assets.

This position requires deep technical and clinical data expertise, cross-domain integration, and a passion for high-quality, reproducible data workflows. Competitive base pay and benefits are offered.

Qualifications

• MS/PhD in Bioinformatics, Data Engineering, or Computer Science.
• 5+ years of data pipeline experience in life sciences or neuroscience.
• Hands-on with clinical data formats (CDISC SDTM/ADaM, FHIR, OMOP).
• Experience with multi-omics workflows (proteomics, RNA-seq, metabolomics, single-cell).
• Experience with embedding or vector representations for data integration.
• Proficiency with Nextflow, AWS, and scripting in Python or Bash.
• Familiarity with Snowflake, TileDB, and scientific data formats.
• Knowledge of neuroscience data or clinical trials is a plus.
• Detail-oriented with a focus on data quality and reproducibility.

Responsibilities

• Design scalable data models for AI-ready clinical data across sources.
• Build Nextflow/Tower pipelines with AWS S3, Snowflake, TileDB for omics.
• Create reusable modules to harmonize assay outputs.
• Embed FAIR data principles and compliance into workflows.
• Lead pipeline optimization and code reviews.
• Collaborate with AI/ML teams to deliver AI-ready datasets.
• Mentor junior engineers and standardize workflows.

Skills

Python scripting

Nextflow

AWS

Data modeling

FAIR data principles

Data governance

Cross-domain integration

Education

MS/PhD in Bioinformatics, Data Engineering, or Computer Science

Tools

Snowflake

TileDB

CDISC SDTM/ADaM

FHIR

OMOP

Job description

Johnson & Johnson Innovative Medicine is hiring a Senior Manager, Data Transformation to join the DDSAI team with locations in Cambridge, MA or other U.S. sites. No remote option. The role leads end-to-end data product development for AI-ready assets.

This position requires deep technical and clinical data expertise, cross-domain integration, and a passion for high-quality, reproducible data workflows. Competitive base pay and benefits are offered.