Senior Computational HitGen/LeadGen Scientist (I-II)

ABBVIE; North Chicago (IL); On-site; USD 110,000 - 209,000; Full time

Job summary

AbbVie in the United States seeks a Senior Scientist I–II to advance AI-enabled drug discovery across small molecules. You will identify, develop, and deploy computational hit generation methods, collaborating with chemists, biologists, and other cheminformatics experts to accelerate hit-to-lead campaigns.

The role emphasizes machine learning, modern computing approaches, and Python-based tooling; prior experience in medicinal chemistry and ability to explain complex ideas to non-specialists is

Qualifications

• Extensive ML experience applying chemical/biological data modeling.
• Strong background in cheminformatics and computational chemistry.
• Proficient in Python and scientific computing workflows.

Responsibilities

• Identify and deploy computational hit generation methods for project goals.
• Collaborate with chemists, biologists, and computational experts to design molecules.
• Communicate rationale for methods and design strategies clearly to teams.
• Develop workflows for predictive modeling of binding and PK properties.

Skills

Machine learning

Python

Chemoinformatics

Communication

Education

PhD in relevant field

MS in relevant field

BS in relevant field

Tools

Python

ML frameworks

Job description

AbbVie in the United States seeks a Senior Scientist I–II to advance AI-enabled drug discovery across small molecules. You will identify, develop, and deploy computational hit generation methods, collaborating with chemists, biologists, and other cheminformatics experts to accelerate hit-to-lead campaigns.

The role emphasizes machine learning, modern computing approaches, and Python-based tooling; prior experience in medicinal chemistry and ability to explain complex ideas to non-specialists is