Senior Computational Chemist

Placements24; United States; Remote; USD 140,000 - 190,000; Full time

Benefits offered by this job

Bonuses

Remote-friendly environment

Stock options

Job summary

Placements24 is seeking a Senior Computational Chemist to join its remote research team. You will design and execute molecular modeling studies, QSAR analyses, and virtual screening to advance drug discovery and development.

Collaborate with medicinal chemists, biologists, and pharmacologists to translate computational insights into experiments, while maintaining and evolving computational tools and pipelines in a fully remote setup.

Qualifications

• Ph.D. in Computational Chemistry, Cheminformatics, Physical Chemistry, or related field.
• Minimum of 5 years of professional experience in computational chemistry, particularly in drug discovery.
• Proficiency in molecular modeling software and structure-based drug design.

Responsibilities

• Perform molecular modeling, virtual screening, and QSAR studies.
• Develop and validate computational methods for predicting molecular properties, binding affinities, and ADMET characteristics.
• Design novel molecular entities using cheminformatics and molecular modeling tools for drug discovery programs.
• Collaborate closely with medicinal chemists, biologists, and pharmacologists to integrate computational insights into experimental design.
• Analyze and interpret large datasets from computational simulations and experimental results.
• Contribute to the development and maintenance of computational chemistry software and databases.

Skills

Python programming

Data analysis

Collaboration

Education

Ph.D. in Computational Chemistry or related field

Tools

Schrödinger

MOE

GROMACS

Job description

About the Role

Our client is seeking a highly skilled and experienced Senior Computational Chemist to join their innovative research team, operating entirely remotely. This role is essential for advancing drug discovery and development through the application of advanced computational chemistry techniques. You will be responsible for designing and executing molecular modeling studies, virtual screening, and property prediction to guide experimental efforts. This is an exceptional opportunity for a seasoned computational chemist to lead impactful projects, collaborate with a distributed team of scientists, and contribute to the development of novel therapeutic agents, enjoying the full benefits of a remote-first work environment.

Key Responsibilities

• Perform molecular modeling, virtual screening, and quantitative structure-activity relationship (QSAR) studies.
• Develop and validate computational methods for predicting molecular properties, binding affinities, and ADMET characteristics.
• Design novel molecular entities using cheminformatics and molecular modeling tools for drug discovery programs.
• Collaborate closely with medicinal chemists, biologists, and pharmacologists to integrate computational insights into experimental design.
• Analyze and interpret large datasets from computational simulations and experimental results.
• Contribute to the development and maintenance of computational chemistry software and databases.

Requirements

• Ph.D. in Computational Chemistry, Cheminformatics, Physical Chemistry, or a related field.
• Minimum of 5 years of professional experience in computational chemistry, particularly in drug discovery.
• Proficiency in molecular modeling software (e.g., Schrödinger, MOE, GROMACS) and structure-based drug design.
• Strong understanding of quantum mechanics, statistical mechanics, and physical organic chemistry principles.
• Experience with programming languages (e.g., Python) and data analysis techniques.

Benefits

• Highly competitive salary and performance-based bonuses.
• Comprehensive health, dental, and vision insurance.
• Stock options and long-term incentive plans.
• Fully remote position with flexible working hours.
• Access to advanced computational resources and collaborative platforms.