Senior Clinical Trial Manager - Global Operations Lead

Equillium, Inc.; San Diego (CA); On-site; USD 150,000 - 210,000; Full time

Job summary

Equillium, Inc. in San Diego seeks a Senior Clinical Trial Manager to lead planning, execution, and closeout of Phase I–III studies, ensuring timelines, budget, and regulatory compliance across the portfolio.

You will coordinate with Clinical Development, Data Management, Regulatory, Medical Writing, and CROs, oversee start‑up activities, site activations, and risk management, while upholding quality and inspection readiness.

Qualifications

• Bachelor's degree in Life Sciences, Nursing, or a related scientific discipline required.
• Advanced degree preferred.
• 8+ years of clinical research experience within the biotechnology, pharmaceutical, or CRO industry, including at least 3 years of clinical trial management responsibility.
• Proven experience leading global Phase I-III clinical trials from start-up through closeout.
• Strong knowledge of ICH‑GCP, FDA, EMA, and global clinical trial regulations.

Responsibilities

• Lead the operational planning, execution, and closeout of Phase I-III clinical trials, ensuring delivery on time, within budget, and in compliance with regulations and procedures.
• Serve as the primary operational lead and central point of coordination across multiple functional areas.
• Provide operational input into protocol development, study design, and enrollment strategies.
• Develop and maintain study timelines, forecasts, risk management plans, and KPIs.
• Oversee start-up activities including vendor selection, site activation, contracting support, and enrollment readiness.
• Monitor trial progress and drive issue resolution and escalation of critical challenges.
• Contribute to process improvements and SOP development.

Education

Bachelor's degree in Life Sciences, Nursing, or a related scientific discipline

Advanced degree

Job description

Equillium, Inc. in San Diego seeks a Senior Clinical Trial Manager to lead planning, execution, and closeout of Phase I–III studies, ensuring timelines, budget, and regulatory compliance across the portfolio.

You will coordinate with Clinical Development, Data Management, Regulatory, Medical Writing, and CROs, oversee start‑up activities, site activations, and risk management, while upholding quality and inspection readiness.