Senior Clinical Trial Manager

Scorpion Therapeutics; Palo Alto (CA); On-site; USD 150,000 - 230,000; Full time

Job summary

Scorpion Therapeutics is seeking a Senior Clinical Trial Manager to lead global oncology Phase 2/3 trials (NSCLC and CRC) from start-up to closeout. The role emphasizes strategic trial planning, CRO oversight, site selection, enrollment, monitoring, risk management, data quality, and inspections readiness.

You will ensure regulatory compliance with GCP and ICH guidelines while mentoring clinical operations staff and fostering cross-functional collaboration across geographies.

Qualifications

• Bachelor's degree in life sciences or related field.
• 8–10+ years in clinical operations with 7+ years managing international oncology trials at Phase II/III.
• Experience in clinical data review, regulatory interactions, and vendor oversight.
• Willingness to travel up to 20%.

Responsibilities

• Oversee global oncology Phase 2/3 trials from start-up to closeout.
• Develop study plans and ensure CRO activities align with timelines.
• Lead risk mitigation and quality assurance, including data quality and safety monitoring.
• Mentor and develop clinical operations staff.
• Ensure regulatory compliance and GCP/ICH standards.
• Travel up to 20% as required.

Skills

Clinical operations

Global trial management

Data review

Regulatory interactions

Vendor oversight

Education

Bachelor's degree in life sciences

Job description

Role:

Senior Clinical Trial Manager overseeing global oncology Phase 2/3 trials, including NSCLC and colorectal cancer, with responsibilities spanning study start-up to closeout, CRO oversight, and inspection readiness. The role involves strategic leadership in site selection, enrollment, monitoring, risk management, and data quality, ensuring regulatory compliance and quality standards (GCP, ICH).

Responsibilities:

Responsibilities include developing study plans, managing CRO activities, leading risk mitigation, and mentoring clinical operations staff.

Requirements:

Bachelor's in life sciences or related field; 8-10+ years in clinical operations, with at least 7+ years managing international oncology trials at Phase II/III; proficiency in clinical data review, regulatory interactions, and vendor oversight; ability to travel up to 20%.

Preferred skills:

Preferred skills include deep knowledge of drug development, GCP, and ICH guidelines, leadership in complex studies, and excellent organizational and communication skills.

High-value specifics:

Oncology (NSCLC, CRC), Phase 2/3, international scope, CRO management, inspection preparedness, and development of clinical trial strategies.

Work setup:

Travel up to 20%, based on project needs.