Senior Clinical PM - 175659 - 176206

Piper Companies; United States; Remote; USD 170,000 - 200,000; Full time

Job summary

Piper Companies is seeking an experienced Senior Clinical Project Manager to support a growing biotech and clinical research organization in the United States. The role directs phase I–IV trials, coordinating sponsors, CROs, sites, and vendors to achieve milestones on time and on budget.

Ideal candidates bring 8+ years in clinical project management within biotech/pharma/CRO settings, strong ICH-GCP and FDA knowledge, and experience managing multinational studies.

Qualifications

• 8+ years of clinical project management experience in biotech, pharma, or CRO environments.
• Experience managing trials in Cardiovascular, MASH, Hepatology, Obesity, or Dermatology.
• Strong knowledge of ICH-GCP guidelines, FDA regulations, and global trial operations.
• Experience managing CROs, vendors, budgets, timelines, and multinational studies.
• Bachelor's degree required; advanced degree preferred.

Responsibilities

• Direct planning, execution, and oversight of Phase I–IV clinical trials to ensure on-time delivery and regulatory compliance.
• Serve as primary liaison among sponsors, CROs, sites, vendors, and stakeholders to drive milestones.
• Monitor progress, identify risks, and implement mitigation strategies to maintain quality and performance.
• Oversee study timelines, enrollment metrics, vendor activities, and financial tracking.
• Lead cross-functional teams through protocol implementation, database lock, and closeout activities.

Skills

Clinical project management

Budget & timelines management

Cross-functional leadership

Education

Bachelor's degree

Advanced degree in Life Sciences/Public Health/Nursing

Job description

Piper Companies is seeking a Senior Clinical Project Manager to support a growing organization in the biotechnology and clinical research industry.

Responsibilities of the Senior Clinical Project Manager include:

• Direct the planning, execution, and oversight of Phase I-IV clinical trials, ensuring studies are delivered on schedule, within budget, and in compliance with regulatory requirements.
• Serve as the primary liaison between sponsors, CROs, clinical sites, vendors, and cross-functional stakeholders to drive study objectives and milestones.
• Monitor trial progress, identify operational risks, and implement mitigation strategies to maintain study quality and performance.
• Oversee study timelines, enrollment metrics, vendor activities, and financial tracking to support successful clinical program execution.
• Lead cross-functional study teams and provide strategic guidance throughout protocol implementation, database lock, and study closeout activities.

Requirements of the Senior Clinical Project Manager include:

• 8+ years of clinical project management experience within biotechnology, pharmaceutical, or CRO environments.
• Proven experience managing clinical trials within Cardiovascular, MASH, Hepatology, Obesity, and/or Dermatology therapeutic areas.
• Strong knowledge of ICH-GCP guidelines, FDA regulations, and global clinical trial operations.
• Experience managing CROs, vendors, budgets, timelines, and multinational clinical studies.
• Bachelor's degree required; advanced degree in Life Sciences, Public Health, Nursing, or a related discipline preferred.

Compensation for the Senior Clinical Project Manager include:

• $170,000-200,000 annually plus bonus
• Full Comprehensive Benefits: Health, Vision, Dental, PTO, Paid Holiday and Sick Leave if Required by Law.
• Fully remote work environment.
• This job opens for applications on 10/16/2026. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords: senior clinical project manager, clinical project manager, clinical operations, cardiovascular, MASH, metabolic dysfunction-associated steatohepatitis, hepatology, liver disease, obesity, dermatology, clinical trials, CRO management, ICH-GCP, remote, biotechnology, pharmaceutical