Senior Chemist

Quadratic 3D, Inc.; Boston (MA); On-site; USD 80,000 - 130,000; Full time

Job summary

An innovative firm is seeking a passionate PhD-level synthetic chemist to lead the discovery of small molecules for next-generation 3D printing resins. This exciting role involves rapid exploration of chemical space through organic synthesis, focusing on structure-property relationships with diverse photochemistry. Ideal candidates will have a strong background in synthetic and physical organic chemistry, with a proven ability to drive projects from conception to completion. Join a dynamic team that values creativity and collaboration in a fast-paced environment, where your contributions will significantly impact cutting-edge materials applications.

Qualifications

• PhD in Organic Chemistry or BS in Chemistry with significant discovery experience.
• Strong expertise in synthetic and physical organic chemistry with publications.

Responsibilities

• Design and troubleshoot synthetic routes for lead candidates.
• Characterize candidates using various analytical techniques.

Skills

Synthetic Chemistry

Physical Organic Chemistry

Data Analysis Tools

Communication Skills

Organizational Skills

Time Management

Collaboration

Education

PhD in Organic Chemistry

BS in Chemistry with 5+ years experience

Tools

UPLC

NMR Spectroscopy

UV/Vis Spectroscopy

IR Spectroscopy

Mass Spectrometry

Computational Chemistry Tools (e.g. DFT)

Job description

Description

We are seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation 3D printing resins. Similar to a drug discovery role, this position involves rapid exploration of chemical space through organic synthesis to develop structure-property relationships. However, our feedback loops take only days rather than months or years, and the structure-property relationships involve diverse photochemistry. This role is particularly appealing to synthetic chemists with a passion for physical organic chemistry. Our process uses a small amount of each lead candidate, so synthetic creativity is not limited by the scalability concerns that usually narrow the available chemical space in materials applications.

Responsibilities:

• Design, refine, and troubleshoot small molecule synthetic routes, with a focus on divergent or modular approaches to rapidly generate lead candidates.
• Characterize lead candidates via UPLC, NMR, UV/Vis and IR spectroscopy, and mass spectrometry.
• Contribute to the development of high-throughput analytical capabilities, small molecule databases, and virtual libraries.
• Work closely with analytical chemists and chemical engineers to establish structure-property relationships in formulations containing lead candidates.

Minimum Qualifications:

• PhD in Organic Chemistry or BS in Chemistry and 5+ years of experience in a small molecule discovery role.
• Candidates should have strong expertise in both synthetic and physical organic chemistry, demonstrated through publications and other activities.
• Significant experience designing and executing multi-step synthetic routes.
• Extensive experience with modern computing and data analysis tools relevant to synthetic chemistry.
• Excellent communication, organizational, and time management skills.
• Demonstrated ability to independently drive an idea from conception to project completion.
• Evidence of strong collaboration and teamwork talents/skills.
• Strong publication record, both as lead author and as contributor to other projects.

Preferred Qualifications:

• Expertise in photochemistry and/or radical chemistry.
• Experience with synthesis of heterocyclic and/or extended aromatic systems, especially those relevant to organic (opto)electronics. Experience with cheminformatics and/or computational chemistry tools (e.g. DFT) relevant to the production of structure-property relationships.

Additional Information:

• Travel: Occasional travel may be required from time to time
• Location: Boston, Massachusetts

We value diversity in our company and are an Equal Opportunity Employer.