Senior Chemical Development Engineer

Placements24; United States; Teletrabalho; USD 140 000 - 180 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Health insurance

Retirement plan

Remote work support

Professional development opportunities

Resumo da oferta

Placements24 seeks a Senior Chemical Development Engineer to drive the design and scale-up of innovative pharmaceutical synthesis routes in a fully remote role. You will lead lab experiments, apply process simulation, and work with a world-class R&D team to bring APIs from concept to scale-up.

You will develop robust, scalable processes for pilot and commercial manufacturing, perform hazard analyses, and mentor junior staff, all while leveraging advanced simulation tools in a remote setting.

Qualificações

• Master's degree or PhD in Chemical Engineering or Organic Chemistry.
• Minimum of 8 years of experience in process development and scale-up within the pharmaceutical or fine chemical industry.
• Strong understanding of organic synthesis, reaction kinetics, and thermodynamics.
• Proven experience in designing and optimizing multi-step synthesis routes.
• Proficiency in process simulation software (Aspen Plus,gPROMS).
• Experience with Design of Experiments (DoE) and statistical analysis.
• Excellent problem-solving and creative approach to technical challenges.
• Strong project management and organizational abilities.
• Exceptional written and verbal communication skills, particularly in technical report writing.
• Ability to work independently and manage multiple projects in a remote setting.

Responsabilidades

• Lead the development of new chemical synthesis processes for pharmaceutical intermediates and APIs.
• Design and execute laboratory experiments to optimize reaction conditions, yields, and purity.
• Develop scalable and robust processes suitable for pilot plant and commercial manufacturing.
• Perform process hazard analyses and develop safety protocols for new processes.
• Utilize process simulation and modeling software to predict process performance and identify potential issues.
• Collaborate with analytical chemists to develop and validate analytical methods for process monitoring.
• Prepare comprehensive technical reports, development plans, and regulatory submission documents.
• Troubleshoot and resolve technical challenges during process development and scale-up activities.
• Mentor junior engineers and chemists involved in process development projects.

Conhecimentos

Process development

Scale-up

Organic synthesis

Reaction kinetics

Thermodynamics

Multi-step synthesis

DoE

Statistical analysis

Project management

Technical report writing

Remote work

Formação académica

Master's degree or PhD in Chemical Engineering or Organic Chemistry

Ferramentas

Aspen Plus

gPROMS

Descrição da oferta de emprego

About the Role

Our client, a forward-thinking pharmaceutical ingredients manufacturer, is seeking a Senior Chemical Development Engineer for their operations near Welkom . This role is dedicated to the research, development, and scale-up of novel chemical synthesis routes. As a fully remote position, you will leverage advanced simulation tools and collaborate virtually with a world-class R&D team to bring new products from laboratory concept to pilot plant production. This is an exciting opportunity to contribute to groundbreaking pharmaceutical advancements while enjoying the flexibility of remote work. You will be instrumental in designing robust and efficient manufacturing processes, ensuring scalability and economic viability. Your expertise will drive innovation and enhance our client's pipeline of active pharmaceutical ingredients (APIs).

Key Responsibilities

• Lead the development of new chemical synthesis processes for pharmaceutical intermediates and APIs.


• Design and execute laboratory experiments to optimize reaction conditions, yields, and purity.


• Develop scalable and robust processes suitable for pilot plant and commercial manufacturing.


• Perform process hazard analyses and develop safety protocols for new processes.


• Utilize process simulation and modeling software to predict process performance and identify potential issues.


• Collaborate with analytical chemists to develop and validate analytical methods for process monitoring.


• Prepare comprehensive technical reports, development plans, and regulatory submission documents.


• Troubleshoot and resolve technical challenges during process development and scale-up activities.


• Mentor junior engineers and chemists involved in process development projects.


• Stay current with emerging technologies and methodologies in pharmaceutical process development.

Requirements

• Master's degree or PhD in Chemical Engineering or Organic Chemistry.


• Minimum of 8 years of experience in process development and scale-up within the pharmaceutical or fine chemical industry.


• Strong understanding of organic synthesis, reaction kinetics, and thermodynamics.


• Proven experience in designing and optimizing multi-step synthesis routes.


• Proficiency in process simulation software (e.g., Aspen Plus, gPROMS).


• Experience with Design of Experiments (DoE) and statistical analysis.


• Excellent problem-solving skills and a creative approach to technical challenges.


• Strong project management and organizational abilities.


• Exceptional written and verbal communication skills, particularly in technical report writing.


• Ability to work independently and manage multiple projects in a remote setting.

Benefits

Our client offers a competitive salary, comprehensive remote work support, and significant opportunities for professional growth. You will be part of an innovative R&D environment with a focus on cutting-edge pharmaceutical development. The fully remote nature of this role provides unparalleled flexibility. Our client provides access to advanced virtual collaboration tools, encourages participation in leading scientific conferences, and supports further education. We offer a robust benefits package, including health, dental, and vision insurance, along with a generous retirement plan. Be a key contributor to life-saving medicines while enjoying a flexible and rewarding career.