Senior CADD Scientist

Genesis Therapeutics Inc.; San Diego (CA); On-site; USD 80,000 - 140,000; Full time

Job summary

An innovative firm is seeking a Senior CADD Scientist to join a world-class computational chemistry team in San Diego. This role focuses on revolutionizing drug discovery through advanced machine learning and biophysical simulations. The successful candidate will work closely with scientists in a state-of-the-art lab, employing cutting-edge AI-powered tools to guide drug discovery programs. This position offers a dynamic environment that encourages innovation, collaboration, and quick iteration. Join a forward-thinking team committed to making significant advancements in the pharmaceutical industry and enjoy a competitive compensation package along with comprehensive health benefits.

Benefits

Competitive Pay

Health Care Plans

Stock Option Eligibility

401(k) Plan

Open PTO Policy

Paid Company Holidays

Free lunch and snacks

Qualifications

• PhD in Computational Chemistry or related field with industry experience.
• Deep understanding of drug design and protein-ligand interactions.

Responsibilities

• Utilize AI-powered CADD tools for small molecule drug discovery.
• Collaborate with medicinal chemists and ensure seamless information flow.

Skills

Computational Chemistry

Structure-based Drug Design

Protein-ligand Interactions

Molecular Design

Virtual Screening

ADMET Prediction

Collaboration

Education

PhD in Computational Chemistry

PhD in Structural Biology

PhD in Organic Chemistry

PhD in Medicinal Chemistry

Tools

MOE

PyMOL

Schrodinger Suite

Job description

Genesis Therapeutics is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Senior CADD Scientist to join our on-site discovery team in San Diego, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US.

What You Will Do (Key Responsibilities)

• Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents.
• Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts.
• Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches.
• Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making.
• Adapt to a fast-paced environment where innovation and quick iteration are encouraged.

What you’ll bring

• PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD.
• Deep understanding of structure-based drug design and protein-ligand interactions.
• Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite.
• Minimum of 2+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs.

What we offer

• Competitive Pay
• Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees)
• Stock Option Eligibility
• 401(k) Plan
• Open PTO Policy
• Paid Company Holidays
• Free lunch and snacks at our offices