Senior Biomarker Scientist: Assay Development for Trials

Vertex Pharmaceuticals; Boston (MA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Annual bonus

Equity awards

Student loan repayment

Commuting subsidy

Charitable donations matching

401(k)

Job summary

Vertex Pharmaceuticals seeks a strategic, hands-on Biomarkers Senior Research Lab Scientist to develop and optimize biomarker assays for clinical trials. The candidate will design and execute experiments to identify and characterize novel biomarkers in human biofluids and tissues.

You will work closely with Research, Quality, and Biomarker Leads to support alignment across ongoing biomarker research activities in a fast-paced, collaborative environment.

Qualifications

• Ph.D. or equivalent degree with 2-5 years of relevant post-doctoral employment experience, or
• Masters degree with 5+ years of relevant employment experience, or
• Bachelor's degree with 8+ years of relevant employment experience

Responsibilities

• Design and execute method development activities for innovative biomarker assays intended for use as primary, secondary, or exploratory endpoints in clinical trials
• Evaluate assay feasibility and strategies for the measurement of novel biomarkers in relevant biological matrices, including human biofluids and tissues
• Troubleshoot technical challenges related to assay development, validation, and implementation across technologies and disease areas
• Support the generation and characterization of critical reagents across assay types as needed
• Partner internally and externally to evaluate CROs and support transfer, validation, and implementation of internally developed assays with external vendors
• Generate and analyze experimental data, and interpret and present results to internal stakeholders and project teams
• Collaborate effectively across multidisciplinary teams to support biomarker research goals

Skills

Method development

Assay validation

Immunoassays

Western blot

Protein labeling

Molecular biology

Cell biology

Data interpretation

Flow cytometry

Education

Ph.D. or equivalent degree

Master’s degree (5+ years experience)

Bachelor’s degree (8+ years experience)

Job description

Vertex Pharmaceuticals seeks a strategic, hands-on Biomarkers Senior Research Lab Scientist to develop and optimize biomarker assays for clinical trials. The candidate will design and execute experiments to identify and characterize novel biomarkers in human biofluids and tissues.

You will work closely with Research, Quality, and Biomarker Leads to support alignment across ongoing biomarker research activities in a fast-paced, collaborative environment.