Biomarker Assay Scientist—Lab Research for Clinical Trials

Vertex Pharmaceuticals Inc (US); Boston (MA); On-site; USD 102,000 - 154,000; Full time

Benefits offered by this job

On‑site work

Job summary

Vertex Pharmaceuticals is seeking a hands‑on Biomarkers Research Lab Scientist to develop and optimize biomarker assays that support clinical trials. You will design and execute experiments to characterize novel biomarkers in human biofluids and tissues, collaborating closely with the Biomarkers lab team and with Research, Quality, and Biomarker Leads.

The ideal candidate has strong laboratory experience, excellent communication, and a collaborative approach to drive assay readiness and data

Qualifications

• Ph.D. or equivalent with 0–3 years post‑doctoral experience, or Master’s with 3+ years, or Bachelor’s with 6+ years relevant experience.
• Hands‑on experience developing ligand binding assays for translational or clinical applications.
• Strong lab experience in molecular and cell biology; proven collaboration in multidisciplinary teams.

Responsibilities

• Develop and optimize biomarker assays for clinical studies through hands‑on lab work.
• Characterize biomarkers in biofluids and tissues and assess assay feasibility.
• Conduct mock validations and support data packages for assay readiness.
• Assist with assay transfer to CROs and external labs including handoffs and troubleshooting.
• Analyze and present experimental results to internal stakeholders and project teams.

Skills

Ligand binding assays

Immunoassays

ELISA

Molecular biology

Cell biology

Data interpretation

Scientific presentation

Education

Ph.D. or equivalent

Master’s degree or equivalent

Bachelor’s degree or equivalent

Tools

qPCR

ddPCR

NGS

Flow cytometry

Western blot

Protein labeling

Job description

Vertex Pharmaceuticals is seeking a hands‑on Biomarkers Research Lab Scientist to develop and optimize biomarker assays that support clinical trials. You will design and execute experiments to characterize novel biomarkers in human biofluids and tissues, collaborating closely with the Biomarkers lab team and with Research, Quality, and Biomarker Leads.

The ideal candidate has strong laboratory experience, excellent communication, and a collaborative approach to drive assay readiness and data