Lead Translational Imaging & Spatial Profiling Scientist

Novartis

Cambridge (MA)

On-site

USD 139,000 - 283,000

Full time

9 days ago
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Job summary

Novartis in Cambridge, MA is seeking a Senior Principal Scientist/Associate Director to lead a small group of biologists with advanced imaging expertise. You will drive integration of spatial proteomics and imaging technologies to enable target discovery and validation across disease areas.

The role blends bench science with leadership, mentoring matrix teams, and shaping translational profiling capabilities using imaging, spatial biology, and multi-omics.

Qualifications

  • PhD in Biology, Cell and Molecular Biology, or related life sciences with 7+ years in drug discovery.
  • Hands-on experience with cellular/tissue models and advanced microscopy (confocal, super-resolution).
  • Experience leading scientists and influencing cross-functional teams in a matrix environment.

Responsibilities

  • Lead development and application of translational biology, imaging, and profiling strategies across the drug discovery pipeline.
  • Design and implement assays and workflows leveraging imaging, spatial biology, and proteomics.
  • Maintain hands-on scientific presence in experimental design, assay development, and data interpretation.
  • Generate biological insights into disease and therapeutic mechanisms, tissue targeting, pharmacology, and translational biomarkers.
  • Mentor and develop scientists, foster collaboration, and communicate findings to project teams and leadership.

Skills

Leadership
Imaging expertise
Translational biology
Cross-functional teamwork
Experimental biology
Data interpretation
AI imaging

Education

PhD in Biology or related life sciences

Job description

Novartis in Cambridge, MA is seeking a Senior Principal Scientist/Associate Director to lead a small group of biologists with advanced imaging expertise. You will drive integration of spatial proteomics and imaging technologies to enable target discovery and validation across disease areas.

The role blends bench science with leadership, mentoring matrix teams, and shaping translational profiling capabilities using imaging, spatial biology, and multi-omics.

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