Senior Bioinformatics Scientist, Cancer Immunotherapy

Novello Therapeutics; Georgia; On-site; USD 110,000 - 150,000; Full time

Job summary

Novello Therapeutics seeks a highly motivated Scientist or Senior Scientist in Bioinformatics to advance our cryptic antigen discovery platform. This hands-on computational biologist will lead analyses of multi-omics data and build scalable pipelines to support antigen discovery and validation.

The ideal candidate has deep experience in immunopeptidomics or MS data analysis, a strong interest in cancer immunotherapy, and thrives in an entrepreneurial environment.

Qualifications

• Ph.D. in Bioinformatics, Computational Biology, Genomics, or related field (or equivalent industry experience).
• 1+ year (Scientist) or 3+ years (Senior Scientist) of relevant industry experience.
• Strong experience with proteomics and/or immunopeptidomics workflows.
• Experience analyzing mass spectrometry data (highly preferred).
• Experience integrating multi-omics data and mining existing datasets.
• Familiar with data analysis methods and artifacts.
• Proficiency in Python and/or R and command-line tools.
• Experience in cancer immunology or oncology antigen discovery preferred.
• Outstanding written and verbal communication skills.
• Highly collaborative, team-oriented, in a fast-paced environment.

Responsibilities

• Lead design and implementation of computational workflows to identify cancer-restricted cryptic peptides.
• Build and maintain scalable computing architecture (cloud and HPC) for high-throughput data.
• Implement secure, cost-effective data storage and retrieval for large datasets.
• Identify, re-analyze and integrate large public datasets including immunopeptidomics.
• Collaborate with immunology, protein engineering, and antibody discovery teams.
• Stay current with methods and data resources in immunopeptidomics and proteogenomics.
• Present findings to leadership and contribute to reports and IP.

Skills

Bioinformatics

Immunopeptidomics

Mass spectrometry

Python

R

Multi-omics

Cloud computing

HPC

Data integration

Communication

Teamwork

Education

PhD in Bioinformatics/Computational Biology/Genomics

Equivalent industry experience

Tools

Command-line

HPC

Cloud platforms

Job description

Novello Therapeutics seeks a highly motivated Scientist or Senior Scientist in Bioinformatics to advance our cryptic antigen discovery platform. This hands-on computational biologist will lead analyses of multi-omics data and build scalable pipelines to support antigen discovery and validation.

The ideal candidate has deep experience in immunopeptidomics or MS data analysis, a strong interest in cancer immunotherapy, and thrives in an entrepreneurial environment.