Senior Bioinformatics Scientist: Cancer Genomics & MRD

Personalis; Fremont (CA); Hybrid; USD 158,000 - 190,000; Full time

Benefits offered by this job

Medical Insurance

Dental & Vision

401(k) Match

ESPP

Tuition Reimbursement

Paid Time Off

Commuter Benefits

EV Charging Stations

Onsite Gym

Wellness Benefits

Job summary

Personalis in Fremont, CA seeks a Senior Bioinformatics Scientist to develop and apply cell-free and solid tumor cancer genomics products. You will collaborate with software and lab teams to apply liquid biopsy solutions to large cohorts and profile patient response to therapy.

This role advances genomics-based precision medicine for immuno-oncology, trials, diagnostics, and therapeutics across pharma, biotech, hospitals and clinicians. Strong publication record is valued.

Qualifications

• Ph.D. in bioinformatics, genomics, or related field.
• Experience managing large multi-participant projects.
• Experience with cancer liquid biopsy analysis.
• Experience with survival analysis.
• Proficiency with Python or R.
• Experience with cancer genomics and variant detection.
• Experience publishing and presenting scientific results.

Responsibilities

• Plan, develop, and manage scientific collaborations applying liquid biopsy and solid tumor products.
• Build upon NeXT Personal MRD liquid biopsy platform and related products.
• Collaborate cross-functionally to translate findings into cutting-edge products.
• Design and execute projects to demonstrate performance of cell-free platforms.
• Model large genomics datasets to generate biological and clinical insights.
• Publish results and present at conferences on DNA and immuno-oncology.

Skills

Survival analysis

Cancer genomics

Variant detection

Scientific publishing

Education

Ph.D. in bioinformatics/genomics or related field

Tools

Python

R

Job description

Personalis in Fremont, CA seeks a Senior Bioinformatics Scientist to develop and apply cell-free and solid tumor cancer genomics products. You will collaborate with software and lab teams to apply liquid biopsy solutions to large cohorts and profile patient response to therapy.

This role advances genomics-based precision medicine for immuno-oncology, trials, diagnostics, and therapeutics across pharma, biotech, hospitals and clinicians. Strong publication record is valued.