Senior Biochemist, DNA Sequencing & Biophysics

Pacific Biosciences; United States; On-site; USD 129,000 - 193,000; Full time

Job summary

PacBio is seeking a Senior Scientist to join an interdisciplinary team addressing biochemical challenges to advance our DNA sequencing technology. The successful candidate will contribute through hands-on laboratory experimentation, biochemical assay development, experimental design, and data analysis.

We seek a PhD holder with 2–5 years of related experience, strong problem‑solving, and excellent communication skills.

Qualifications

• PhD required in Biochemistry, Biophysics, Molecular Biology, Chemistry, or related field.
• 2–5 years related experience, may include post‑doc.
• Hands-on biochemical/biophysical experimentation experience, including assay development and troubleshooting.
• Excellent communication and collaboration skills.

Responsibilities

• Design and execute hypothesis-driven experiments to support sequencing chemistry development.
• Develop, optimize, and troubleshoot biochemical and biophysical assays.
• Design, source, and use custom DNA substrates and specialized reagents.
• Analyze data, assess reproducibility, and present findings in meetings.
• Collaborate across disciplines to address technical challenges with biochemical insights.
• Maintain accurate records and contribute to experimental planning.

Skills

Biochemical experiments

Assay development

Data analysis

Independent work

Interpersonal skills

AI tools

Education

PhD in Biochemistry, Biophysics, Molecular Biology, Chemistry, or related field

Job description

PacBio is seeking a Senior Scientist to join an interdisciplinary team addressing biochemical challenges to advance our DNA sequencing technology. The successful candidate will contribute through hands-on laboratory experimentation, biochemical assay development, experimental design, and data analysis.

We seek a PhD holder with 2–5 years of related experience, strong problem‑solving, and excellent communication skills.