Senior Associate Scientist, High Throughput Protein Production

Xaira Therapeutics, Inc.; South San Francisco (CA); Sur place; USD 101 000 - 126 000; Plein temps

Résumé du poste

Xaira Therapeutics, Inc. is seeking a Senior Associate Scientist to join the High-Throughput Protein Production team in the San Francisco Bay Area.

You will focus on automating, scaling, and improving protein expression and purification workflows for antibody modalities. The role emphasizes implementing automation platforms, integrating workflow systems, and developing data-driven methods to track production data.

Qualifications

• BS/MS in Biochemistry or Molecular Biology with 5+ years of protein expression/purification experience.
• Experience with high-throughput mammalian expression systems and protein purification techniques.
• Familiarity with automation, liquid handling, robotic platforms, and scripting (Python/R) is a plus.

Responsabilités

• Operate and optimize high-throughput protein production workflows for antibody modalities.
• Implement and integrate automation platforms, ensuring seamless workflow.
• Develop and validate methods for automated protein purification.
• Troubleshoot automation issues, improve efficiency and yield.
• Stay current with advancements in automation and protein production.
• Collaborate across disciplines to optimize workflows.
• Design a data management system to track protein production data.
• Analyze data and identify areas for improvement.
• Prepare reports and presentations.

Connaissances

Protein expression

Protein purification

Automation

High-throughput systems

Python/R scripting

Data analysis

Team collaboration

Independent work

Formation

Biochemistry / Molecular Biology

Outils

Automated liquid handling

Robotic platforms

Automation software

Description du poste

Senior Associate Scientist, High Throughput Protein Production

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role

We are seeking a highly motivated Senior Associate Scientist to join our High-Throughput Protein Production team and play a key role in automating, streamlining, and scaling up protein production processes. This position offers a unique opportunity to leverage your expertise in protein expression and purification along with your passion for automation to develop and implement cutting-edge workflows.

About You

You are an enthusiastic protein sciences team who takes pride in your bench execution skills. Your passion lies in drug discovery and developing novel treatments for patients. You are conscientious, detail-oriented, and organized. Collaboration comes naturally to you, and you thrive in a fast-paced environment and pushing the boundaries of what is possible is the norm.

What You\'ll Do and Learn

• Operate and optimize high-throughput protein production workflows for antibody modalities.


• Implement and integrate automation platforms, ensuring seamless workflow.


• Develop and validate methods for automated protein purification.


• Troubleshoot automation issues, improve efficiency and yield.


• Stay current with advancements in automation and protein production.


• Collaborate across disciplines to optimize workflows.


• Design a data management system to track protein production data.


• Analyze data and identify areas for improvement.


• Prepare reports and presentations.

Qualifications

• BS/MS in Biochemistry, Molecular Biology, or a related field with5+ years of experience in protein expression and purification.


• Strong operational understanding of automation, work cells, and protein science principles and methodologies.


• Experience with high-throughput mammalian expression systems.


• Experience with protein purification techniques (e.g., affinity chromatography, various polishing steps).


• Proven ability to design and optimize protein purification protocols.


• Experience with automated liquid handling systems and robotic platforms (preferred).


• Experience with programming skills (e.g., Python, R) for scripting automation workflows (a plus).


• Excellent analytical and problem-solving skills.


• Strong communication and interpersonal skills.


• Ability to work independently and as part of a team.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $101,000 - $126,000 annually; however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Xaira Therapeutics’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

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