Senior Associate Scientist, Gene Delivery and Editing Process Development

Scorpion Therapeutics; Seattle (WA); On-site; USD 90,000 - 150,000; Full time

Benefits offered by this job

Health coverage

PTO & holidays

Job summary

Scorpion Therapeutics seeks a scientist to support upstream viral vector development and process optimization for engineered T cell manufacturing. You will contribute to tech transfer, process characterization, and cross-functional collaborations with internal and external teams.

The role requires hands-on experience with mammalian cell culture, DOE, and data analysis, along with strong technical writing and communication skills to present results effectively.

Qualifications

• BS or MS with hands-on upstream experience in cell culture and viral vectors.
• Experience with DOE and statistical software (e.g., JMP).
• Strong written and oral communication skills and ability to train others.
• Ability to multitask and coordinate within a team to drive projects.

Responsibilities

• Support upstream viral vector development/optimization in mammalian culture.
• Assist process development and tech transfer for viral vector manufacturing.
• Contribute to late-phase development and process characterization.
• Design, plan, execute and analyze DOE-based experiments.

Skills

DOE

Oral communication

Technical writing

Team coordination

JMP

Education

Bachelor's degree in life sciences

Tools

Mammalian cell culture

Stirred tank bioreactors

AEX chromatography

Tangential Flow Filtration

Job description

Position Summary

• Support process development, production, and characterization of early and late-stage viral vectors (lentiviral vectors and/or adeno-associated viruses) for engineered T cell manufacturing.
• Provide technical subject matter expertise for internal/external collaborators across tech transfer, process characterization, and pre-clinical/clinical process lifecycle management.

Key Responsibilities

• Perform hands‑on upstream viral vector development/optimization (mammalian cell culture, stirred tank bioreactors, transient transfection); downstream experience (clarification, AEX chromatography, Tangential Flow Filtration) is a bonus.
• Support process and technology development for viral vector manufacturing platforms.
• Support late-phase development, including process characterization.
• Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles.
• Maintain documentation in an electronic lab notebook.
• Summarize/present data and communicate progress.
• Author technical documents (protocols and internal development reports).
• Follow lab safety rules and practices.

Qualifications & Experience

• B.S. with 5+ years or M.S. with 2+ years of hands‑on upstream experience (downstream is a plus).
• Ability to use DOE approaches; interpret results using statistical software (e.g., JMP).
• Independently motivated; multitask, problem‑solve, train others on lab operations, and coordinate within a team.
• Strong interest in biological mechanisms of cell/gene therapy products and impact on patients.
• Clear oral presentation and technical writing skills.

Benefits (as stated)

• Health coverage (medical, pharmacy, dental, vision); wellbeing support; 401(k); disability and life insurance; other listed financial protections.
• Paid time off (flexible/unlimited for US exempt employees; or 160 hours annual paid vacation for certain Phoenix/Puerto Rico/Rayzebio employees), plus national holidays.