Senior Analytical Scientist

Advantage Technical; Menlo Park (CA); On-site; USD 85,000 - 100,000; Full time

Benefits offered by this job

Medical, dental, vision

401(k) Retirement Savings Plan

Employee Assistance Program

Commuter/Parking Accounts

Health Savings Account

AD&D Insurance

Job summary

Advantage Technical is seeking a Senior Analytical Scientist in Menlo Park, CA to advance peptide discovery using nanoLC-MS/MS and Thermo Orbitrap instruments. The role focuses on high-sensitivity analyses and method development to support cutting-edge research.

Responsibilities include developing NanoLC-MS workflows, acquiring and interpreting MS/MS data for peptide sequencing, maintaining instruments, and collaborating with cross-functional teams.

Qualifications

• MS/PhD in Analytical Chemistry, Biochemistry, Mass Spectrometry or related field.
• Equivalent industry experience considered.
• 3+ years hands-on nano-flow LC-MS/MS on Thermo instrumentation.

Responsibilities

• Perform high-sensitivity nano-flow LC-MS/MS analysis of peptide samples.
• Develop and optimize nanoLC-MS/MS methods and MS/MS acquisition parameters.
• Configure and operate Thermo Orbitrap XL and Thermo Dionex UltiMate 3000 NanoLC system.
• Analyze and interpret LC-MS/MS data for peptide sequence identification.
• Perform instrument maintenance, calibration, troubleshooting, and performance optimization.
• Document analytical methods, results, and recommendations.
• Collaborate with scientific teams to support peptide hit identification.

Skills

NanoLC-MS/MS

Orbitrap MS

Xcalibur software

Peptide sequencing

Method development

Data analysis

Education

MS/PhD in Analytical Chemistry

Tools

Thermo Orbitrap

Dionex UltiMate 3000

Job description

Senior Analytical Scientist

Location: Menlo Park, CA

Pay Rate: $85,000-100,000

Advance Peptide Discovery with Cutting-Edge Mass Spectrometry

Staffmark is seeking an experienced Senior Analytical Scientist for a consulting opportunity supporting an innovative peptide discovery program. If you have hands-on expertise with Thermo Orbitrap mass spectrometers, nanoLC-MS/MS method development, and peptide sequence identification, this is an excellent opportunity to work on high-impact research with potential for recurring project assignments.

Education Requirements

• M.S. or Ph.D. in Analytical Chemistry, Biochemistry, Mass Spectrometry, or a related scientific field
• Equivalent industry experience will be considered

Experience Requirements

• 3+ years of hands-on experience with nano-flow LC-MS/MS on Thermo instrumentation
• Experience operating and troubleshooting Thermo Orbitrap mass spectrometers and Xcalibur software
• Strong knowledge of peptide MS/MS fragmentation and database-based sequence identification
• Experience developing and optimizing nanoLC-MS workflows

Job Duties

• Perform high-sensitivity nano-flow LC-MS/MS analysis of peptide samples
• Develop and optimize nanoLC-MS/MS methods and MS/MS acquisition parameters
• Configure and operate a Thermo Orbitrap XL and Thermo Dionex UltiMate 3000 NanoLC system
• Analyze and interpret LC-MS/MS data for peptide sequence identification
• Perform instrument maintenance, calibration, troubleshooting, and performance optimization
• Resolve nanoLC system issues involving flow paths, columns, emitters, and electrospray stability
• Document analytical methods, results, and recommendations
• Collaborate with scientific teams to support peptide hit identification

Physical Capabilities

• Ability to work in a laboratory environment and operate precision analytical instrumentation
• Strong attention to detail and ability to manage multiple project priorities

Benefits

• Medical, dental, vision, and pet insurance
• 401(k) Retirement Savings Plan
• Employee Assistance Program (EAP)
• Commuter/Parking Accounts
• People Perks
• Health Savings Account (HSA)
• AD&D Insurance

The base pay range listed reflects what we reasonably expect to offer for this role. Actual pay may vary based on location, experience, and performance. Depending on the position, benefits may include medical, dental, and vision coverage; retirement and savings plans; paid holidays and time off; supplemental insurance; and additional wellness or incentive programs.

About Us

Advantage Technical connects top- talent in technology, engineering, and technical fields with forward-looking companies.

Advantage Technical is an equal opportunity employer. All applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status, or any other legally protected status. Advantage Technical offers reasonable accommodations for qualified individuals with disabilities; contact your local branch for inquiries. Advantage Technical is an E-Verify employer. See our Privacy Notice for Candidates and Employees/Contractors at https://smgroupna.com/privacy-notice-for-candidates-and-employees-contractors.