Senior Analytical Chemist - Solid-State Characterization Lead

Sanofi EU; Cambridge (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Sanofi is seeking a Senior Analytical Chemist in Cambridge, MA to lead solid-state characterization efforts, focusing on polymorphism and salt screening. You will actively design and implement methods using XRPD, DSC, TGA and related techniques, supporting development projects across functions.

The role emphasizes independent reporting, collaboration across teams, and applying AI-driven approaches to optimize decisions in drug development.

Qualifications

• PhD in chemistry, pharmaceutical science, material science, or related fields with minimum 3 years of postdoctoral experience in a pharma or biopharma environment.
• In-depth experience with XRPD, DSC, TGA for solid-state characterization.
• Expertise in polymorphism/salt selection and understanding of powder and particle properties.
• In-depth understanding of pharmaceutical solid-state properties.

Responsibilities

• Lead polymorphism studies and polymorph screening.
• Design and conduct salt selection studies and stability assessment.
• Act as the solid-state representative on development projects.
• Develop and implement analytical methods using XRPD, DSC, TGA, SEM, Raman, IR, and laser granulometry.
• Provide physical characterization support to internal partner teams.
• Use computational tools to perform Crystal Structure Prediction studies.
• Generate technical reports independently.
• Develop effective collaborations within project teams and analytics groups.
• Introduce AI/modeling and automation in analyses.
• Promote scientific excellence through presentations and publications.

Skills

Polymorphism

Salt selection

Crystal structure prediction

Solid-state properties

Education

PhD in chemistry/pharmaceutical science/material science

Tools

XRPD

DSC

TGA

SEM

Raman

IR

Laser granulometry

Job description

Sanofi is seeking a Senior Analytical Chemist in Cambridge, MA to lead solid-state characterization efforts, focusing on polymorphism and salt screening. You will actively design and implement methods using XRPD, DSC, TGA and related techniques, supporting development projects across functions.

The role emphasizes independent reporting, collaboration across teams, and applying AI-driven approaches to optimize decisions in drug development.