Senior ADME Scientist — Enzymology & PK Translation

Pfizer; Groton (CT); Hybrid; USD 106,000 - 177,000; Full time

Benefits offered by this job

Bonus target 15% of base salary

Comprehensive benefits package

Relocation assistance may be available

Job summary

Pfizer seeks a scientist to join the Quantitative Metabolism team within ADME Sciences to advance small molecule programs from discovery through development. You will design and oversee enzymology and ADME studies, translating data into actionable recommendations to guide project decisions with risk assessment.

This lab-based, onsite role requires advanced degree with significant ADME experience and strong collaboration and communication skills.

Qualifications

• PhD in a related science discipline with 4+ years industry ADME experience OR MS with 9+ years OR BS with 12+ years.
• Knowledge of enzymology/drug metabolism principles and PK predictions.
• Experience leading complex ADME workstreams and providing scientific recommendations.

Responsibilities

• Serve as the ADME scientific owner for project questions and align recommendations with stakeholder priorities.
• Lead design, execution, and interpretation of enzymology studies addressing clearance and DDI risk.
• Integrate in vitro ADME data to identify liabilities and propose mitigation strategies.
• Provide scientific ownership for risk assessments to support project decisions.
• Lead experiments with scientific rigor and data quality; mentor scientists.

Skills

Enzymology knowledge

ADME project leadership

Scientific communication

Mentoring/scientific coaching

Education

PhD in related science

MS in related science

BS in related science

Job description

Pfizer seeks a scientist to join the Quantitative Metabolism team within ADME Sciences to advance small molecule programs from discovery through development. You will design and oversee enzymology and ADME studies, translating data into actionable recommendations to guide project decisions with risk assessment.

This lab-based, onsite role requires advanced degree with significant ADME experience and strong collaboration and communication skills.