Senior Account Executive - US/UK

HeliCal; Boston (MA); Hybrid; USD 90,000 - 150,000; Full time

Benefits offered by this job

Equity

Direct impact

Leadership collaboration

Job summary

Helical is building the AI-native biology platform and seeks a Senior Account Executive to drive strategic enterprise sales across pharma and biotech. You will own multi-stakeholder deals, convert initial opportunities into long-term partnerships, and articulate value to scientific and executive buyers.

You will engage with discovery, computational biology, data science, and R&D leaders, shaping the commercial motion and helping Helical scale its market presence in a fast-growing field.

Qualifications

• Proven enterprise sales experience and track record of closing complex B2B deals.
• Ability to land new logos and build a strategic enterprise pipeline.
• Excellent communication, qualification, negotiation, and closing skills.
• Strong ability to engage with scientific and technical stakeholders.
• Comfort operating in a fast-moving, early-stage environment.

Responsibilities

• Own the full sales cycle from prospecting to close.
• Land new logos across pharma, biotech, and life sciences.
• Build and manage a strategic enterprise pipeline.
• Navigate multi-stakeholder sales cycles across scientific and executive buyers.
• Translate Helical’s AI-native biology platform into clear customer value.
• Partner with founders, product, science, and customer teams.

Skills

Enterprise sales

Closing complex deals

Hunter mentality

Stakeholder management

Communication skills

Job description

Senior Account Executive

Hybrid | Full-time
London | Boston | Luxembourg

Helical is building the AI-native lab for biology — replacing slow, costly wet lab experimentation with scalable, virtual discovery. Our platform is already deployed with leading global pharma, enabling teams to run millions of experiments in days, not years.

We’re hiring a Senior Account Executive to drive new business across leading pharmaceutical and biotechnology companies.

This is a strategic enterprise sales role focused on landing new logos, owning complex sales cycles, and turning initial opportunities into long-term, multi-program partnerships. You’ll sell into scientific and technical teams across discovery, computational biology, data science, R&D, and executive leadership.

You will:

• Own the full sales cycle from prospecting to close
• Land new logos across pharma and biotech
• Build and manage a strategic enterprise pipeline
• Navigate complex, multi-stakeholder sales cycles
• Engage with scientific, technical, procurement, and executive buyers
• Translate Helical’s AI-native biology platform into clear customer value
• Partner with founders, product, science, and customer teams
• Help refine sales messaging, qualification, and go-to-market playbooks
• Represent Helical at industry events and customer meetings

We’re looking for someone with:

• Proven enterprise sales experience as an AE or Senior AE
• Track record of closing complex B2B deals
• Experience selling into pharma, biotech, life sciences, healthcare, AI, data, or scientific software markets
• Strong new business/hunter mentality
• Ability to engage credibly with technical and scientific stakeholders
• Excellent communication, qualification, negotiation, and closing skills
• Comfort operating in a fast-moving, early-stage environment
• Interest in how AI is transforming drug discovery and biological research

What we offer:

• Product already deployed with leading global pharma
• High ownership and direct impact
• Close collaboration with founders and senior leadership
• Opportunity to shape the commercial motion of a category-defining AI biology company
• Competitive salary, equity, and benefits