Scientist - Systems Mass Spectrometry

Stowers Institute for Medical Research; Kansas City (MO); On-site; USD 70,000 - 110,000; Full time

Job summary

The Stowers Institute and its Systems Mass Spectrometry Department seek a Scientist to develop and apply leading-edge mass spectrometry–based multi-omics approaches to support research programs. You will assist researchers in designing and implementing MS experiments that generate impactful, collaborator-driven outcomes.

The role requires strong organizational, communication, and independent-working skills, with the ability to coordinate efforts with colleagues and collaborators, while

Qualifications

• PhD or MSc in chemistry/biochemistry/molecular biology or related field.
• Several years of demonstrated experience in a scientific laboratory setting.
• Strong communication and presentation skills.

Responsibilities

• Lead design and implementation of mass spectrometry experiments for collaborators.
• Process samples and perform data acquisition for protein IDs, PTMs, crosslinked peptides, metabolites, and lipids.
• Analyze and visualize large MS datasets; prepare project reports and figures for publications.
• Coordinate with collaborators; write sections of manuscripts and grant applications.
• Maintain thorough documentation and data management through LIMS; adapt pipelines to collaborators’ needs.
• Stay current in MS-based multi-omics by reading literature and attending conferences.
• Assist with maintenance of mass spectrometers and HPLC systems and coordinate service calls.
• Contribute to internal courses/workshops for trainees.
• Other duties as assigned.

Skills

Organizational skills

Multitasking

Communication skills

Written communication

Verbal communication

Attention to detail

Education

PhD or MSc in chemistry/biochemistry/molecular biology

Tools

Mass spectrometry

HPLC systems

Job description

The Systems Mass Spectrometry Department at the Stowers Institute has an immediate opening for a Scientist to adopt, adapt, and develop leading-edge mass spectrometry-based multi-omics approaches to support research programs at the Institute. The primary role of this position is to assist researchers in the design and implementation of mass spectrometry experiments for impactful outcomes relevant to collaborators’ goals. The successful candidate will have excellent organizational and multi-tasking skills, be detail-oriented, have superior written and verbal communication skills, and be able to work independently while still coordinating efforts with their collaborators and colleagues.

Main Responsibilities:

• Meeting with collaborators early and often during the lifetime of a project to discuss goals, expectations, and limitations, and suggest the appropriate analytical workflows and controls for successful outcomes.
• Performing timely and accurate sample processing and data acquisition to provide identification and quantitation of proteins and post translational modifications, crosslinked peptides, as well as other biological analytes of interest (metabolites and lipids).
• Processing, analyzing, and visualizing large-scale mass spectrometry datasets.
• Writing project reports and explaining results and conclusions to collaborators.
• Writing sections of manuscripts and providing tables and figures for use in publications or grant/fellowships applications.
• Keeping detailed, and accurate documentation of experimental procedures, data, and analysis, including meticulous sample tracking and data management through LIMS.
• Adapting and developing new and emerging analytical pipelines relevant to collaborators’ needs.
• Staying up to date in leading-edge biological mass spectrometry through reading literature, attending conferences, and participating in workshops.
• Participating in the troubleshooting, maintenance, and repair of high-end mass spectrometers and their HPLC systems, as well as coordinating service calls as necessary.
• Assisting with the development of internal courses and workshops for Stowers trainees
• Other duties as assigned.
• A Ph.D. or Master’s degree in chemistry, biochemistry, molecular biology, or a related field.
• Several years of demonstrated experience working in a scientific laboratory setting.
• Strong communication and presentation skills.