Scientist, Synthetic Biology: Programmable RNA Circuits

Strand Therapeutics; Boston (MA); On-site; USD 120,000 - 132,000; Full time

Benefits offered by this job

Health insurance

Dental coverage

Open PTO

Onsite lunch catering

Commuter support

Job summary

Strand Therapeutics is seeking a Scientist of Synthetic Biology to design RNA-based genetic circuits for drug discovery and development. You will independently conceive, conduct, and critically analyze experiments with minimal supervision, applying fundamental design principles to create programmable genetic systems.

The role offers a fast-paced, entrepreneurial environment in Boston, with a focus on advancing STRX programs and contributing to a growing team of scientists.

Qualifications

• PhD in Biomedical Engineering, Bioinformatics, or equivalent required.
• 1-2 years of professional research experience in industrial and/or academia required.
• Ability to plan, design and execute experiments and communicate findings to diverse audience.
• Experience with cellular and molecular biology techniques like molecular cloning, qPCR, mammalian cell culture and transfection.
• Prior experience with flow cytometry, image analysis, and automation equipment is a plus.
• Hands-on experience with in vitro transcription of mRNA required.
• Adaptable to change in a dynamic early-stage environment.
• Strong team player with excellent communication and independent work; detail oriented.
• Excellent organizational skills and attention to detail.

Responsibilities

• Design and develop synthetic genetic constructs to enable programmable, cell-type specific gene expression.
• Build and test engineered circuits for desirable phenotypes in relevant cell systems in vitro, validating designs.
• Plan experiments using techniques including molecular cloning, transfection, flow cytometry, ELISA, qPCR, and Western blot.
• Maintain proper records in electronic notebooks and contribute to writing protocols.
• Communicate methods and results to teammates and work closely with cross-functional teams.

Skills

RNA design

Mammalian cell culture

Molecular cloning

qPCR

Flow cytometry

Education

PhD in Biomedical Engineering or Bioinformatics

Tools

Mammalian cell transfection

ELISA

Western blot

Job description

Strand Therapeutics is seeking a Scientist of Synthetic Biology to design RNA-based genetic circuits for drug discovery and development. You will independently conceive, conduct, and critically analyze experiments with minimal supervision, applying fundamental design principles to create programmable genetic systems.

The role offers a fast-paced, entrepreneurial environment in Boston, with a focus on advancing STRX programs and contributing to a growing team of scientists.