RNA Platform Scientist — Programmable eRNA Design

Sail Biomedicines; Cambridge (MA); On-site; USD 98,000 - 125,000; Full time

Job summary

Sail Biomedicines in Cambridge, MA, seeks a Scientist, Platform RNA Sciences, to advance Endless RNA technology through hypothesis-driven experiments and high-throughput screens. You will maximize circularization and RNA stability, translating discovery into potential therapies.

Applicants should have a PhD in molecular biology or biochemistry or an MS with extensive RNA tech experience, strong data-analysis skills, and the ability to manage multiple projects in a fast-paced, collaborative

Qualifications

• Ph.D. in Molecular Biology or Biochemistry, or M.S. with 6+ years in RNA technologies.
• Strong background in RNA biology with hands-on techniques listed.
• Experience with data analysis and information-management tools (Excel, Prism, R, Jira).
• Excellent problem-solving, multitasking, collaboration and communication.

Responsibilities

• Conceive and conduct pooled and array screens to improve eRNA designs.
• Design hypothesis-driven experiments using state-of-the-art RNA biology.
• Evaluate and develop alternative circularization strategies.
• Determine circularization efficiency and impurity levels with analytics.
• Produce high-quality data, write SOPs and reports, and document work.

Skills

RNA biology

Molecular biology

Data analysis tools

Education

Ph.D. in Molecular Biology or Biochemistry

M.S. with 6+ years in RNA technologies

Tools

IVT

RNA purification

oligo-dT purification

column chromatography

capillary gel electrophoresis

RT-qPCR

RNA-seq

Nanopore sequencing

Excel

GraphPad Prism

R

JMP

SnapGene

Benchling

Smartsheet

Jira

Job description

Sail Biomedicines in Cambridge, MA, seeks a Scientist, Platform RNA Sciences, to advance Endless RNA technology through hypothesis-driven experiments and high-throughput screens. You will maximize circularization and RNA stability, translating discovery into potential therapies.

Applicants should have a PhD in molecular biology or biochemistry or an MS with extensive RNA tech experience, strong data-analysis skills, and the ability to manage multiple projects in a fast-paced, collaborative