Scientist, Stem Cell Engineering

Colossal Biosciences; Dallas (TX); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Medical, dental, and vision coverage

Paid time off and company holidays

Flexible spending accounts (FSA)

Company matched 401k retirement plan

Paid parental leave at 100% salary for

12 weeks

Education reimbursement

Job summary

Colossal Biosciences in Dallas, TX, seeks a talented stem cell biologist to advance avian embryonic stem cell culture, genome editing, and embryo reintroduction using cutting‑edge technologies. You will collaborate with a lab team to develop protocols and contribute to project progress.

The ideal candidate holds a PhD and expertise in embryonic stem cell culture, microscopy-based embryo manipulation, and molecular biology; strong communication and problem‑solving skills are essential.

Qualifications

• PhD in biological sciences or related field.
• Experience in embryonic stem cell culture and embryo manipulation under a microscope.

Responsibilities

• Culture avian embryonic stem cells and test culture conditions.
• Dissect avian embryos to derive stem cell cultures.
• Characterize and QC stem cell cultures.
• Inject stem cells into avian blastodiscs.
• Assess editing efficiency via NGS sequencing.
• Attend lab meetings and prepare progress reports.
• Maintain organized lab records.

Skills

Embryonic stem cells

Embryo manipulation

Stem cell derivation & culture

Molecular biology

Flow cytometry / immunostaining

Communication & problem-solving

Education

PhD in Biological Sciences

Job description

An affiliate of Colossal Biosciences is looking for a talented stem cell biologist with an interest in the manipulation of avian embryonic stem cells. You will work closely with other lab team members in efforts to innovate on protocols of avian stem cell culture, genome editing, and reintroduction into embryos using cutting edge technologies.

This position is based in Dallas, TX. Relocation assistance is available.

Duties and Responsibilities:

• Culture avian embryonic stem cells, test novel cell culture conditions, transfect cells, sort monoclonal cell lines, screen and expand cells according to latest protocols and newly developed approaches
• Using a dissection microscope, collect avian blastodiscs from avian embryos and derive stem cell cultures
• Characterize and QC avian stem cell cultures
• Inject stem cells into avian blastodiscs
• Work with team members to assess efficiency of editing through NGS sequencing approaches
• Attends lab meetings, prepares reports, and presentations on the progress of projects
• Great organizational skills and excellent laboratory record maintenance

Required Skills and Abilities:

• Experience with embryonic stem cell cultures
• Experience manipulating embryos under a microscope
• Experience in cell line derivation, culture, propagation, and transfection methodologies
• Experience in molecular biology (eg, nucleic acid and protein extraction, gel electrophoresis)
• Experience with flow cytometry, immunostaining, cell microscopy
• Strong written and oral communication skills, as well as creative problem-solving skills

Education and Experience:

• PhD in biological sciences, cell biology, bioengineering, molecular biology, genetics, or any science related field.

What Colossal Offers Full-Time Employees:

• Medical, dental, and vision coverage
• Excellent paid time off and company holidays so you can rest and recharge
• Flexible spending accounts (FSA)
• Company matched 401k retirement plan
• Paid parental leave at 100% salary for up to 12 weeks
• Education reimbursement
• An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.

Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace.

We welcome people from all backgrounds as well as celebrate and support diversity.

We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:

• #1 on the 50 Best Startups to Work For in Dallas in 2023!
• 100 Best Midsize Places to Work in Dallas in 2024 & 2025
• 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.

Built In 2026 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.

Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!