Scientist, Nucleic Acid Technologies — mRNA & ASO

Genentech; South San Francisco (CA); On-site; USD 103,000 - 192,000; Full time

Benefits offered by this job

Discretionary annual bonus

On-site laboratory position

Job summary

Genentech’s Therapeutic Modalities and Technologies group seeks a scientist to join the Nucleic Acid Technologies team in South San Francisco. You will contribute to design and generation of modalities across mRNA, ASO/siRNA, and novel approaches, advancing therapeutic programs through optimized workflows and new capabilities.

Candidates should have a strong background in molecular biology and cell culture, experience with NGS library prep and data analysis, and excellent collaboration skills

Qualifications

• Master's or PhD in Biological Sciences with 1+ years of relevant industry or academic experience.
• Hands-on experience with molecular biology techniques (sequence design, cloning, PCR, qRT-PCR) and mammalian cell culture.
• Practical experience with NGS library preparation and data analysis platforms.
• Strong written and verbal communication and collaboration skills.

Responsibilities

• Design and execute experiments leveraging innovative molecular and cellular technologies to advance therapeutic programs across mRNA and nucleic acid-based medicines.
• Optimize experimental workflows and develop new capabilities to increase testing efficiency and dataset dimensionality.
• Serve as an incubator for emerging technologies, conducting early assessments of high-priority biological questions that enable future opportunities.
• Perform techniques such as qRT-PCR, NGS library preparation, mammalian cell culture, transfection/electroporation, and cell-based screening.
• Analyze complex datasets using platforms and programming tools (Benchling, Snapgene, R, Python) and present findings to cross-functional partners.
• Collaborate closely with team members and project partners in a fast-paced, high-impact research environment.

Skills

Molecular biology techniques

Mammalian cell culture

Data analysis

Education

Master's or PhD in Biological Sciences (Genetics, Cell Biology, Molecular Biology, Biochemistry, Genome Engineering)

Tools

Benchling

SnapGene

R

Python

Job description

Genentech’s Therapeutic Modalities and Technologies group seeks a scientist to join the Nucleic Acid Technologies team in South San Francisco. You will contribute to design and generation of modalities across mRNA, ASO/siRNA, and novel approaches, advancing therapeutic programs through optimized workflows and new capabilities.

Candidates should have a strong background in molecular biology and cell culture, experience with NGS library prep and data analysis, and excellent collaboration skills