Senior Scientist, Nucleic Acids Payload Engineering

Genentech

San Diego (CA)

On-site

USD 108,100 - 200,700

Full time

14 days+

Get more replies from employers

Send a job-specific resume in minutes.

Benefits offered by this job

Relocation assistance
Annual bonus

Job summary

Genentech seeks a Senior Scientist in San Diego to lead efforts in developing our non‑viral gene delivery platform. You will drive molecular engineering to enhance DNA delivery and nuclear shuttling, with a focus on reducing DNA immunogenicity and enabling high‑throughput screening in mammalian cells.

The role requires a PhD in a related field with post‑doc/industry experience, expertise in nucleic acid manipulation and cloning, and strong collaboration across teams to advance in vivo cell and

Qualifications

  • PhD in a relevant field and post‑doc or industry experience
  • Experience with high‑throughput library screening in mammalian systems
  • Advanced nucleic acid manipulation and cloning methods as listed in the job description

Responsibilities

  • Advance non‑viral gene delivery platform through hands‑on lab work and concept validation
  • Direct and perform rigorous hypothesis‑driven projects and screening to achieve feasibility milestones for in‑vivo portfolios
  • Collaborate across cross‑functional teams to translate research into clinical and drug discovery frameworks

Skills

High-throughput screening
Molecular biology
Nucleic acid manipulation
Molecular cloning
qPCR
Western blot
Mammalian cell biology
ddPCR

Education

PhD in Molecular Biology

Tools

IVT
Golden Gate cloning
Gibson assembly
SDM

Job description

Genentech seeks a Senior Scientist in San Diego to lead efforts in developing our non‑viral gene delivery platform. You will drive molecular engineering to enhance DNA delivery and nuclear shuttling, with a focus on reducing DNA immunogenicity and enabling high‑throughput screening in mammalian cells.

The role requires a PhD in a related field with post‑doc/industry experience, expertise in nucleic acid manipulation and cloning, and strong collaboration across teams to advance in vivo cell and

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Senior Scientist, Nucleic Acids Payload Delivery
Senior Scientist, Nucleic Acids Payload Delivery

F. Hoffmann-La Roche AG • San Diego (CA)

On-site
USD 108,000 - 201,000
Relocation benefits
Discretionary annual bonus
Senior Scientist - Nucleic Acids Payload Engineering
Senior Scientist - Nucleic Acids Payload Engineering

F. Hoffmann-La Roche AG • San Diego (CA)

On-site
USD 108,000 - 201,000
Relocation benefits
Discretionary annual bonus
Senior Scientist - Nucleic Acids Payload Engineering
Senior Scientist - Nucleic Acids Payload Engineering

Genentech • San Diego (CA)

On-site
USD 108,000 - 201,000
Relocation assistance
Annual bonus
Scientist I (Gene Therapy/ Cell Cloning)
Scientist I (Gene Therapy/ Cell Cloning)

Dawar Consulting • San Diego (CA)

On-site
USD 63,000 - 68,000
Medical
Dental
Vision
+2
Cell & Gene Therapy R&D Scientist I
Cell & Gene Therapy R&D Scientist I

247Hire • San Diego (CA)

On-site
USD 65,000 - 90,000
Gene Therapy Scientist I: Cell Cloning & IVT
Gene Therapy Scientist I: Cell Cloning & IVT

Dawar Consulting • San Diego (CA)

On-site
Scientist I
Scientist I

247Hire • San Diego (CA)

On-site
USD 65,000 - 90,000
Director, RNA Therapeutics Chemistry & Delivery
Director, RNA Therapeutics Chemistry & Delivery

Ignite Human Capital • San Diego (CA)

On-site
USD 150,000 - 200,000
Medical, dental, and vision insurance
401(k) with matching
Generous PTO
Gene Delivery & Editing Process Development Scientist
Gene Delivery & Editing Process Development Scientist

Bristol Myers Squibb • Seattle (WA)

On-site
USD 88,000 - 107,000
Health Coverage
401(k) plan
Paid Time Off
Lead Scientist, Oligonucleotide Design & Chemistry
Lead Scientist, Oligonucleotide Design & Chemistry

F. Hoffmann-La Roche AG • South San Francisco (CA)

On-site
USD 143,000 - 266,000
Relocation assistance
Annual bonus (discretionary)