Scientist – Neurology, Waltham, MA

BPGbio, Inc.; Waltham (MA); On-site; USD 107,000 - 115,000; Full time

Job summary

BPGbio, Inc. in Waltham, MA, is seeking a Scientist to join the Discovery & Translational Biology Group. The role focuses on molecular and cellular biology, biochemistry, and protein sciences to support target validation and drug discovery.

The candidate will lead lab work, collaborate across teams, and contribute to project goals. The Scientist will develop and optimize assays, analyze data, and report results, while mentoring junior staff and coordinating with CROs as needed. A Ph.D.

Qualifications

• Requires a Ph.D. in neuroscience, biochemistry, or a related field with 1–5 years of postdoctoral experience.
• Strong understanding of neurobiology, cellular metabolism, and neurological disease models.
• Extensive knowledge of neural physiology and systems biology is desirable.
• Solid scientific training/productivity evidenced by high-impact publications.
• Excellent oral and written communication skills with ability to prepare manuscripts.

Responsibilities

• Perform the full spectrum of laboratory activities and independently develop, troubleshoot, and optimize cell-based and biochemical assays.
• Identify, develop, and implement methods for characterization of novel drug targets and their biology.
• Develop proposals and implement assays for potency, target engagement, and mechanism of action of novel compounds.
• Maintain laboratory records, organize data, and write/present comprehensive reports.
• Facilitate interactions with internal groups and external partners/CROs.
• Handle laboratory workflows and participate in project/timeline management.
• Mentor and assist junior team members.
• Other duties as assigned.

Skills

Molecular biology

Cell biology

Biochemistry

Drug discovery

Education

Ph.D. in Neuroscience/Biochemistry

Tools

Western blot

PCR

RT-qPCR

Flow cytometry

Protein purification

Job description

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

Scientist

Discovery & Translational Biology Full Time Waltham, MA, US

10 days ago Requisition ID: 1246

Salary Range: $107,000.00 To $115,000.00 Annually

POSITION SUMMARY:

The Scientist in Neurology is a highly skilled and motivated individual who will be part of an integrated research team within the Discovery & Translational Biology Group. The Scientist will have profound research experience in molecular and cell biology, biochemistry and/or protein sciences applied in the context of drug discovery and biological characterization of novel targets. The Scientist will develop and implement scientific research in the laboratory as well as collaborate with cross-functional groups to support target assessment/validation and drug discovery activities.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Perform the full spectrum of laboratory activities and independently develop, troubleshoot, and optimize cell-based and biochemical assays in support of target validation, drug discovery, and development efforts
• Independently identify, develop, and implement methods for the characterization of novel drug targets and their biology.
• Independently develop proposals and implement assays for assessment of potency, target engagement, and mechanism of action of novel compounds using multiple techniques (e.g., recombinant DNA techniques, RNA purification, Western, PCR, RT-qPCR, protein extraction/purification, IP, flow cytometry, plate-based endpoints).
• Maintain laboratory records and notebook, organize and compile data, and write and present comprehensive reports on results.
• Facilitate interactions with internal groups and external partners/CROs relevant to experimental projects.
• Handle laboratory workflows and participate in project/timeline management.
• Mentor and assist junior team members.
• Other duties as assigned

REQUIREMENTS:

• Requires a Ph.D. in neuroscience, biochemistry, or a related field with 1-5 years of postdoctoral experience.
• Strong understanding of neurobiology, cellular metabolism, and neurological disease models as well as critical thinking and creative problem-solving abilities.
• Extensive knowledge of neural physiology and systems biology is desirable.
• Solid scientific training/productivity as identified through high-impact publications demonstrating creative thinking as well as innovative technical approaches.
• Excellent oral and written communication skills and a proven ability to prepare manuscripts for presentation and publication is required.